To accompany the brand refresh and our renewed focus on giving you better models of human disease, we’re also updating our products and services.

 

Sometimes you need to refocus and that’s exactly what we’re doing. To make it easier for you to find what you need, explore new options, and recognize our products wherever they’re used, we’re updating our products and services.

Everything you’ve always relied on for will still be available – no need to worry about that. It’s just that things will now have a more consistent and recognizable brand, and you may even notice a few extra and improved details.

You’ll now be able to choose from

• axoLines^TM
• axoCells^TM
• axoServices^TM

axoLines^TM: human iPSCs from consenting patients

At the core of everything we offer are our human induced pluripotent stem cells (iPSCs), and these make up our axoLines^TM range. These iPSCs come from fully consenting patients across a spectrum of diseases, such as Alzheimer’s disease, Parkinson’s disease, and amyotrophic lateral sclerosis.

From this starting point, you can start to build models of human disease that are genuinely representative of what we see in vivo.

Currently, you can choose human iPSC donors across fourteen distinct diseases, each with a selection of genetic backgrounds and isogenic controls. Have a look at the disease models available and simply let us know what your research needs.

axoCells™: human iPSC derived cells from healthy donors and patient donors with a particular disease
So that you have access to human cells, to create better models of human diseases and human physiology, our axoCells^TM range includes some of the most used cell types, derived from human iPSCs. Here you’ll find cells from healthy donors, as well as cells from patient donors with a specific type of disease.

axoCells™ from healthy donors

If you’re looking for cells derived from healthy donors, you can choose from

• Neural stem cells
• Ventricular and CiPA-validated atrial cardiomyocytes
• Motor and sensory neurons
• Microglia
• Astrocytes

axoCells™ from patient donors

If you need to model a specific disease, we have iPSC-derived neural stem cells (NSCs) generated from patient donors. This includes

• Alzheimer’s disease patient with APOE4 homozygous mutation
• Alzheimer’s disease patient with Presenilin 1 (PSEN1) L286V mutation
• Alzheimer’s disease patient with Presenilin 1 (PSEN1) A246E mutation
• Alzheimer’s disease patient with Presenilin 1 (PSEN1) M146L mutation
• Huntingdon’s disease patient with CAG repeat expansion 50

axoCells™: media and supplements

Finally, we’ve developed a range of cell media and specialized supplements to work specifically with the cell types you’ll find in our catalog. We designed the supplements, like the Sensory Neuron Maturation Maximizer Supplement, to mimic in vivo signals between your cell of interest and supporting cells, which significantly speeds up maturation times in vitro.

You’ll find the recommended media and supplements on the vast majority of our cell product pages, so you can easily find everything you need all on one page.

axoServices^TM: custom lab services

This is where you can make use of our expertise and have us run custom lab services or even entire iPSC projects.

Through axoServices^TM you can take advantage of the many years we’ve been creating, characterizing, and studying iPSCs and how to get the most out of them. This will save you valuable time by letting us handle the iPSC aspects of your projects. You can choose from

• Multi-electrode array analysis
• Genome editing
• Stem cell reprogramming
• Stem cell differentiation

If you’d like support with a more complex or bespoke project, we have experts on hand to help you understand how we can support you. Just send us a message and we’ll get right back to you.

Better models mean better research

This is an exciting time as we see iPSC-derived cells becoming increasingly popular in research and integrated into the drug development process. We strongly believe that human iPSCs and the cells we can derive from there represent the basis of more powerful and accurate modeling that both industry and academia need. These better models drive better research and better results and we’re proud to be able to support the scientific community with the tools it needs to succeed.