Expansion of CAG repeats in the Huntingtin gene (HTT) produces a mutant version of the huntingtin protein whose presence becomes toxic to brain cells, leading to cell death and underlying the progressive pathology of Huntington’s Disease.
We have six lines derived from Huntington’s Disease patients. They are excellent models for investigating the disease and developing assays to screen potential therapies
Huntington’s Disease Products
Human iPSC-derived neural stem cells from Huntington’s Disease patients.
Please note, CENSOi53-A is an asymptomatic carrier not patient.
Fibroblasts (48 Yr Female)
1.5 million cells