axoServicesTM cellular assays
Outsource your iPSC project to the experts
Cellular assay services
Human iPSC-derived cellular assays for drug discovery and translational research
We provide comprehensive discovery and preclinical specialist services, including small molecule, ASO and AAV testing. Predictive, highly validated disease and safety models support research, drug discovery and translational research.
We specialize in cellular imaging, flow cytometry, MEA, protein/gene analysis and plate-based assays with a specific emphasis on the quality and communication of assay data.
Our expertise spans assay development, target validation, mode-of-action and safety studies across neuroscience, ophthalmology, cardiovascular and dermatology applications.
We offer a bespoke service to fit your needs
As experts in iPSC projects, we offer a full suite of custom cellular assays to match your research needs.
Our capabilities are as follows:
| Cellular imaging | Flow cytometry | Protein and gene analysis | Plate-based assays |
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We also offer a bespoke MEA (Multi Electrode Array) service with decades of electrophysiology expertise in-house and an industry-leading MEA platform.
If you’d like to explore a custom cellular assay project that isn’t listed above, please get in touch and we can discuss how to best assist you.
Disease area expertise
Neuroscience
Drug candidate, viral delivery vectors and novel mechanism drug toxicity and activity screening using multi-electrode array (MEA), flow cytometry, cellular imaging, plate-based assays and omics.
Ophthalmology
Comprehensive high content screening services for assessment of RPE health and function, including growth factor secretion (VEGF, PEDF), barrier integrity (TEER), phagocytosis, pigmentation and maturity markers, oxidative stress, complement activation, cell viability and apoptosis.
Compound efficacy and toxicity testing using human iPSC-derived retinal organoids, enabling assessment of therapeutic response and mechanism of action. Optimised retinal organoid-based screening systems for retinal toxicity with cell viability (ATP-based assays), morphological assessment, and short- and long-term treatment regimes.
Cardiovascular
Candidate drug testing and cardiac safety assessment using human iPSC-derived cardiomyocyte models. Services and capabilities include evaluation of drug effects on cardiac electrophysiology, contractility, ion channel function, and chamber-specific pharmacological responses.
Dermatology
Outsourced efficacy and toxicity testing using sebocyte, melanocyte, and sensory neuron models, with flexible assay design and physiologically relevant endpoints.
Multiparametric readouts including lipid synthesis, pigmentation, cytokine release, receptor activation, neurite outgrowth, cell viability, and morphology across 96-well and scalable screening formats.
Our approach to collaboration
What does the ideal outsourced scientific project look like? We see ourselves as collaborators, partners, bench scientists and project managers, here to work alongside you to support and accelerate your work. And just like you, we like getting the work done efficiently and effectively, with clear open communication throughout.
We also recognize the trust you put in us to support your work, remove the heavy lifting and ensure your timelines proceed on schedule. Ultimately, we’re all progressing towards the same mission so we would be honored to partner on your research and get closer to delivering better therapies for patients.
Our company operates through its stated values and behaviors of Performance, Accountability, Transparency, Collaboration, Diversity & Inclusion and Integrity. With a dedicated services team, we’re always on hand to support in any way we can.
We hope that we can be of service and welcome your enquiries.
Discuss your project
If you would like to discuss the adoption of iPSC-derived cells into your workflow, or our specialist services provision, please contact us at operations@axolbio.com
