Publications

Publications featuring Axol Bioscience products

Axol Bioscience’s iPSC-derived cellsmedia and supplements feature in thousands of publications. We’ve brought together a list of of publications by product.

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Product Code Product Name PMC DOI Weblink Title Authors Year
ax0015 axoCells™ Human iPSC-Derived Neural Stem Cells, newborn male donor, ≥1.5 million cells PMC9860124 https://doi.org/10.1016/j.stemcr.2022.11.014 http://www.cell.com/article/S2213671122005471/pdf Long-term calcium imaging reveals functional development in hiPSC-derived cultures comparable to human but not rat primary cultures Estévez-Priego E, Moreno-Fina M, Monni E, Kokaia Z, Soriano J, Tornero D. 2023
ax0015 axoCells™ Human iPSC-Derived Neural Stem Cells, newborn male donor, ≥1.5 million cells PMC5415290 https://doi.org/10.1177/2041731417697920 https://journals.sagepub.com/doi/pdf/10.1177/2041731417697920 Adapting tissue-engineered in vitro CNS models for high-throughput study of neurodegeneration. O’Rourke C, Lee-Reeves C, Drake RA, Cameron GW, Loughlin AJ, Phillips JB. 2017
ax0015 axoCells™ Human iPSC-Derived Neural Stem Cells, newborn male donor, ≥1.5 million cells PMC9641809 https://doi.org/10.1186/s13578-022-00916-1 https://cellandbioscience.biomedcentral.com/counter/pdf/10.1186/s13578-022-00916-1 An increase in Semaphorin 3A biases the axonal direction and induces an aberrant dendritic arborization in an in vitro model of human neural progenitor differentiation Ferretti G, Romano A, Sirabella R, Serafini S, Maier TJ, Matrone C. 2022
ax0015 axoCells™ Human iPSC-Derived Neural Stem Cells, newborn male donor, ≥1.5 million cells PMC7498259 https://doi.org/10.7554/elife.58124 https://elifesciences.org/articles/58124 Quantitative mapping of transcriptome and proteome dynamics during polarization of human iPSC-derived neurons. Lindhout FW, Kooistra R, Portegies S, Herstel LJ, Stucchi R, Snoek BL, Altelaar AM, MacGillavry HD, Wierenga CJ, Hoogenraad CC. 2020
ax0016 axoCells™ Human iPSC-Derived Neural Stem Cells, female donor, ≥1.5 million cells PMC4870631 https://doi.org/10.1038/srep26181 https://www.nature.com/articles/srep26181.pdf Physiological maturation and drug responses of human induced pluripotent stem cell-derived cortical neuronal networks in long-term culture Odawara A, Katoh H, Matsuda N, Suzuki I. 2016
ax0016 axoCells™ Human iPSC-Derived Neural Stem Cells, female donor, ≥1.5 million cells 32314760 https://doi.org/10.1039/c9lc01209e https://pubs.rsc.org/en/content/articlepdf/2020/lc/c9lc01209e Development of two-photon polymerised scaffolds for optical interrogation and neurite guidance of human iPSC-derived cortical neuronal networks Crowe JA, El-Tamer A, Nagel D, Koroleva AV, Madrid-Wolff J, Olarte OE, Sokolovsky S, Estevez-Priego E, Ludl AA, Soriano J, Loza-Alvarez P, Chichkov BN, Hill EJ, Parri HR, Rafailov EU. 2020
ax0016 axoCells™ Human iPSC-Derived Neural Stem Cells, female donor, ≥1.5 million cells PMC6629824 https://doi.org/10.3389/fncel.2019.00296 https://www.frontiersin.org/articles/10.3389/fncel.2019.00296/pdf Distinct Conformations, Aggregation and Cellular Internalization of Different Tau Strains Karikari TK, Nagel DA, Grainger A, Clarke-Bland C, Crowe J, Hill EJ, Moffat KG. 2019
ax0016 axoCells™ Human iPSC-Derived Neural Stem Cells, female donor, ≥1.5 million cells PMC7498259 https://doi.org/10.7554/elife.58124 https://elifesciences.org/articles/58124 Quantitative mapping of transcriptome and proteome dynamics during polarization of human iPSC-derived neurons. Lindhout FW, Kooistra R, Portegies S, Herstel LJ, Stucchi R, Snoek BL, Altelaar AM, MacGillavry HD, Wierenga CJ, Hoogenraad CC. 2020
ax0018 axoCells™ Human iPSC-Derived Neural Stem Cells, male donor, ≥1.5 million cells 32350390 https://doi.org/10.1038/s41380-020-0717-5 https://www.nature.com/articles/s41380-020-0717-5 ATP and spontaneous calcium oscillations control neural stem cell fate determination in Huntington’s disease: a novel approach for cell clock research Glaser T, Shimojo H, Ribeiro DE, Martins PPL, Beco RP, Kosinski M, Sampaio VFA, Corrêa-Velloso J, Oliveira-Giacomelli Á, Lameu C, de Jesus Santos AP, de Souza HDN, Teng YD, Kageyama R, Ulrich H. 2021
ax0018 axoCells™ Human iPSC-Derived Neural Stem Cells, male donor, ≥1.5 million cells PMC9647772 https://doi.org/10.1038/s41380-022-01851-w https://www.nature.com/articles/s41380-022-01851-w.pdf Activation of a novel α2AAR-spinophilin-cofilin axis determines the effect of α2 adrenergic drugs on fear memory reconsolidation Saggu S, Chen Y, Cottingham C, Rehman H, Wang H, Zhang S, Augelli-Szafran C, Lu S, Lambert N, Jiao K, Lu XY, Wang Q. 2023
ax0018 axoCells™ Human iPSC-Derived Neural Stem Cells, male donor, ≥1.5 million cells PMC6858358 https://doi.org/10.1038/s41598-019-53414-9 https://www.nature.com/articles/s41598-019-53414-9.pdf Co-stimulation with IL-1β and TNF-α induces an inflammatory reactive astrocyte phenotype with neurosupportive characteristics in a human pluripotent stem cell model system Hyvärinen T, Hagman S, Ristola M, Sukki L, Veijula K, Kreutzer J, Kallio P, Narkilahti S. 2019
ax0018 axoCells™ Human iPSC-Derived Neural Stem Cells, male donor, ≥1.5 million cells PMC5467336 https://doi.org/10.1155/2017/1892612 https://downloads.hindawi.com/journals/np/2017/1892612.pdf Sortilin-Related Receptor Expression in Human Neural Stem Cells Derived from Alzheimer’s Disease Patients Carrying the APOE Epsilon 4 Allele Zollo A, Allen Z, Rasmussen HF, Iannuzzi F, Shi Y, Larsen A, Maier TJ, Matrone C. 2017
ax0018 axoCells™ Human iPSC-Derived Neural Stem Cells, male donor, ≥1.5 million cells PMC10929014 https://doi.org/10.3389/fnmol.2024.1365752 https://www.frontiersin.org/articles/10.3389/fnmol.2024.1365752/pdf?isPublishedV2=False LRRC25 expression during physiological aging and in mouse models of Alzheimer’s disease and iPSC-derived neurons Devadoss D, Akkaoui J, Nair M, Lakshmana MK. 2024
ax0031 axoCells™ Neural Maintenance Media, 500ml PMC8891113 https://doi.org/10.1007/s10571-020-00984-2 https://link.springer.com/content/pdf/10.1007/s10571-020-00984-2.pdf A Progressive Loss of phosphoSer138-Profilin Aligns with Symptomatic Course in the R6/2 Mouse Model of Huntington’s Disease: Possible Sex-Dependent Signaling Baharani A, Wei Z, Roesler WJ, Mousseau DD 2022
ax0031 axoCells™ Neural Maintenance Media, 500ml PMC6331036 https://doi.org/10.1016/j.ab.2018.10.013 https://www.sciencedirect.com/science/article/pii/S0003269718305244/pdfft?md5=f12d39b9e182ba62022ae6f748f54b26&pid=1-s2.0-S0003269718305244-main.pdf Preparation of stable tau oligomers for cellular and biochemical studies Karikari TK, Nagel DA, Grainger A, Clarke-Bland C, Hill EJ, Moffat KG. 2019
ax0031 axoCells™ Neural Maintenance Media, 500ml 26805387 https://doi.org/10.1016/j.nbd.2016.01.007 https://www.sciencedirect.com/science/article/abs/pii/S0969996116300080?via%3Dihub Interplay between TDP-43 and docosahexaenoic acid-related processes in amyotrophic lateral sclerosis Cacabelos D, Ayala V, Granado-Serrano AB, Jové M, Torres P, Boada J, Cabré R, Ramírez-Núñez O, Gonzalo H, Soler-Cantero A, Serrano JC, Bellmunt MJ, Romero MP, Motilva MJ, Nonaka T, Hasegawa M, Ferrer I, Pamplona R, Portero-Otín M. 2016
ax0031 axoCells™ Neural Maintenance Media, 500ml NA https://doi.org/10.1101/2023.09.15.558029 https://www.biorxiv.org/content/biorxiv/early/2023/09/16/2023.09.15.558029.full.pdf Carvedilol suppresses ryanodine receptor-dependent Ca2+ bursts in human neurons bearing PSEN1 variants found in early onset Alzheimer’s disease Atsushi Hori, Tomohiko Ai, Takashi Hato, Haruka Inaba, Kimie Tanaka, Shoichi Sato, Mizuho Okamoto, Yuna Horiuchi, Faith Jessica Paran, Yoko Tabe, Corina Rosales, Wado Akamatsu, Takashi Murayama, Nagomi Kurebayashi, Takashi Sakurai, Takashi Miida, 2023
ax0031 axoCells™ Neural Maintenance Media, 500ml PMC5555676 https://doi.org/10.1128/msphere.00292-17 https://msphere.asm.org/content/msph/2/4/e00292-17.full.pdf Phenotypic Differences between Asian and African Lineage Zika Viruses in Human Neural Progenitor Cells Anfasa F, Siegers JY, van der Kroeg M, Mumtaz N, Stalin Raj V, de Vrij FMS, Widagdo W, Gabriel G, Salinas S, Simonin Y, Reusken C, Kushner SA, Koopmans MPG, Haagmans B, Martina BEE, van Riel D. 2017
ax0031 axoCells™ Neural Maintenance Media, 500ml PMC9761683 https://doi.org/10.1523/jneurosci.1630-22.2022 https://www.jneurosci.org/content/jneuro/42/49/9129.full.pdf The RNA-Binding Protein HuR Is Integral to the Function of Nociceptors in Mice and Humans. Kunder N, de la Peña JB, Lou TF, Chase R, Suresh P, Lawson J, Shukla T, Black B, Campbell ZT. 2022
ax0031 axoCells™ Neural Maintenance Media, 500ml PMC6629824 https://doi.org/10.3389/fncel.2019.00296 https://www.frontiersin.org/articles/10.3389/fncel.2019.00296/pdf Distinct Conformations, Aggregation and Cellular Internalization of Different Tau Strains Karikari TK, Nagel DA, Grainger A, Clarke-Bland C, Crowe J, Hill EJ, Moffat KG. 2019
ax0047 axoCells™ Human FGF2, 100 µg 32537827 https://doi.org/10.1002/adma.202002183 https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/adma.202002183 Lipid-Bilayer-Supported 3D Printing of Human Cerebral Cortex Cells Reveals Developmental Interactions. Zhou L, Wolfes AC, Li Y, Chan DCW, Ko H, Szele FG, Bayley H. 2020
ax0047 axoCells™ Human FGF2, 100 µg PMC8891113 https://doi.org/10.1007/s10571-020-00984-2 https://link.springer.com/content/pdf/10.1007/s10571-020-00984-2.pdf A Progressive Loss of phosphoSer138-Profilin Aligns with Symptomatic Course in the R6/2 Mouse Model of Huntington’s Disease: Possible Sex-Dependent Signaling Baharani A, Wei Z, Roesler WJ, Mousseau DD 2022
ax0047 axoCells™ Human FGF2, 100 µg PMC11083435 https://doi.org/10.1016/j.actbio.2020.02.015 http://manuscript.elsevier.com/S1742706120300945/pdf/S1742706120300945.pdf Probing prodrug metabolism and reciprocal toxicity with an integrated and humanized multi-tissue organ-on-a-chip platform Rajan SAP, Aleman J, Wan M, Pourhabibi Zarandi N, Nzou G, Murphy S, Bishop CE, Sadri-Ardekani H, Shupe T, Atala A, Hall AR, Skardal A. 2020
ax0055 axoCells™ Human iPSC-Derived Sensory Neurons, male donor, ≥0.5 million cells 36244818 https://doi.org/10.1016/j.bja.2022.09.009 https://www.bjanaesthesia.org/action/showPdf?pii=S0007-0912%2822%2900519-0 Use of a human induced pluripotent stem cell-derived dorsal root ganglion neurone model to study analgesics in vitro: proof of principle using lidocaine Smulders PSH, Ten Hoope W, Bernardino Morcillo C, Hermanides J, Hollmann MW, Weber NC. 2022
ax0055 axoCells™ Human iPSC-Derived Sensory Neurons, male donor, ≥0.5 million cells 35478041 https://doi.org/10.1093/toxsci/kfac045 https://academic.oup.com/toxsci/article-pdf/188/1/131/45940430/kfac045.pdf In Vitro Pain Assay Using Human iPSC-Derived Sensory Neurons and Microelectrode Array Odawara A, Shibata M, Ishibashi Y, Nagafuku N, Matsuda N, Suzuki I. 2022
ax0055 axoCells™ Human iPSC-Derived Sensory Neurons, male donor, ≥0.5 million cells PMC10227861 https://doi.org/10.1096/fj.202101933rr https://faseb.onlinelibrary.wiley.com/doi/epdf/10.1096/fj.202101933RR Global analyses of mRNA expression in human sensory neurons reveal eIF5A as a conserved target for inflammatory pain. Chase R, de la Peña JB, Smith PR, Lawson J, Lou TF, Stanowick AD, Black BJ, Campbell ZT. 2022
ax0055 axoCells™ Human iPSC-Derived Sensory Neurons, male donor, ≥0.5 million cells PMC10863150 https://doi.org/10.1186/s41232-024-00319-4 https://inflammregen.biomedcentral.com/counter/pdf/10.1186/s41232-024-00319-4 Novel artificial nerve transplantation of human iPSC-derived neurite bundles enhanced nerve regeneration after peripheral nerve injury Nishijima T, Okuyama K, Shibata S, Kimura H, Shinozaki M, Ouchi T, Mabuchi Y, Ohno T, Nakayama J, Hayatsu M, Uchiyama K, Shindo T, Niiyama E, Toita S, Kawada J, Iwamoto T, Nakamura M, Okano H, Nagoshi N. 2024
ax0058 axoCells™ Sensory Neuron Maximizer Supplement, 1 ml 36244818 https://doi.org/10.1016/j.bja.2022.09.009 https://www.bjanaesthesia.org/action/showPdf?pii=S0007-0912%2822%2900519-0 Use of a human induced pluripotent stem cell-derived dorsal root ganglion neurone model to study analgesics in vitro: proof of principle using lidocaine Smulders PSH, Ten Hoope W, Bernardino Morcillo C, Hermanides J, Hollmann MW, Weber NC. 2022
ax0058 axoCells™ Sensory Neuron Maximizer Supplement, 1 ml 38640063 https://doi.org/10.1016/j.celrep.2024.114129 https://www.cell.com/cell-reports/pdf/S2211-1247(24)00457-1.pdf Macrophage epigenetic memories of early life injury drive neonatal nociceptive priming Dourson AJ, Fadaka AO, Warshak AM, Paranjpe A, Weinhaus B, Queme LF, Hofmann MC, Evans HM, Donmez OA, Forney C, Weirauch MT, Kottyan LC, Lucas D, Deepe GS Jr, Jankowski MP. 2024
ax0058 axoCells™ Sensory Neuron Maximizer Supplement, 1 ml 35478041 https://doi.org/10.1093/toxsci/kfac045 https://academic.oup.com/toxsci/article-pdf/188/1/131/45940430/kfac045.pdf In Vitro Pain Assay Using Human iPSC-Derived Sensory Neurons and Microelectrode Array Odawara A, Shibata M, Ishibashi Y, Nagafuku N, Matsuda N, Suzuki I. 2022
ax0058 axoCells™ Sensory Neuron Maximizer Supplement, 1 ml PMC10802627 https://doi.org/10.1101/2024.01.10.575114 https://www.biorxiv.org/content/10.1101/2024.01.10.575114v1.full.pdf SARS-CoV-2 papain-like protease activates nociceptors to drive sneeze and pain Mali SS, Silva R, Gong Z, Cronce M, Vo U, Vuong C, Moayedi Y, Cox JS, Bautista DM 2024
ax0058 axoCells™ Sensory Neuron Maximizer Supplement, 1 ml 37395585 https://doi.org/10.1111/exd.14870 https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/exd.14870 New human in vitro co-culture model of keratinocytes and sensory neurons like cells releasing substance P with an evaluation of the expression of ZIKV entry receptors: A potent opportunity to test Zika virus entry and to study Zika virus’ infection in neurons? Bocciarelli C, Cordel N, Leschiera R, Talagas M, Le Gall-Ianotto C, Hu W, Marcorelles P, Bellemere G, Bredif S, Fluhr J, Misery L, Lebonvallet N. 2023
ax0072 axoCells™ Motor Neuron Maintenance Media, 200 ml PMC8175425 https://doi.org/10.1038/s41598-021-91203-5 https://www.nature.com/articles/s41598-021-91203-5.pdf Bioengineered model of the human motor unit with physiologically functional neuromuscular junctions. Rimington RP, Fleming JW, Capel AJ, Wheeler PC, Lewis MP. 2021
ax0072 axoCells™ Motor Neuron Maintenance Media, 200 ml PMC10760048 https://doi.org/10.1101/2023.12.12.571328 https://www.biorxiv.org/content/10.1101/2023.12.12.571328v1.full.pdf A high-fidelity CRISPR-Cas13 system improves abnormalities associated with C9ORF72-linked ALS/FTD. McCallister TX, Lim CKW, Terpstra WM, Alejandra Zeballos C M, Zhang S, Powell JE, Gaj T. 2023
ax0072 axoCells™ Motor Neuron Maintenance Media, 200 ml PMC8716921 https://doi.org/10.3389/fnint.2021.792863 https://www.frontiersin.org/articles/10.3389/fnint.2021.792863/pdf Silencing of Activity During Hypoxia Improves Functional Outcomes in Motor Neuron Networks in vitro. Fiskum V, Sandvig A, Sandvig I. 2021
ax0074 axoCells™ Human iPSC-Derived Motor Neurons, ALS (C9ORF72) female donor, ≥2 million cells PMC10760048 https://doi.org/10.1101/2023.12.12.571328 https://www.biorxiv.org/content/10.1101/2023.12.12.571328v1.full.pdf A high-fidelity CRISPR-Cas13 system improves abnormalities associated with C9ORF72-linked ALS/FTD. McCallister TX, Lim CKW, Terpstra WM, Alejandra Zeballos C M, Zhang S, Powell JE, Gaj T. 2023
ax0078 axoCells™ Human iPSC-Derived Motor Neurons, male donor, ≥2 million cells PMC7822896 https://doi.org/10.1038/s41598-021-81335-z https://www.nature.com/articles/s41598-021-81335-z.pdf A directional 3D neurite outgrowth model for studying motor axon biology and disease. Spijkers XM, Pasteuning-Vuhman S, Dorleijn JC, Vulto P, Wevers NR, Pasterkamp RJ. 2021
ax0078 axoCells™ Human iPSC-Derived Motor Neurons, male donor, ≥2 million cells PMC8175425 https://doi.org/10.1038/s41598-021-91203-5 https://www.nature.com/articles/s41598-021-91203-5.pdf Bioengineered model of the human motor unit with physiologically functional neuromuscular junctions. Rimington RP, Fleming JW, Capel AJ, Wheeler PC, Lewis MP. 2021
ax0078 axoCells™ Human iPSC-Derived Motor Neurons, male donor, ≥2 million cells PMC8716921 https://doi.org/10.3389/fnint.2021.792863 https://www.frontiersin.org/articles/10.3389/fnint.2021.792863/pdf Silencing of Activity During Hypoxia Improves Functional Outcomes in Motor Neuron Networks in vitro. Fiskum V, Sandvig A, Sandvig I. 2021
ax0111 axoCells™ Human iPSC-Derived Neural Stem Cells, Alzheimer’s Disease (APOE4 HOM) female donor, ≥1.5 million cells PMC8217363 https://doi.org/10.1007/s00401-021-02315-1 https://link.springer.com/article/10.1007/s00401-021-02315-1 ApoE4 inhibition of VMAT2 in the locus coeruleus exacerbates Tau pathology in Alzheimer’s disease Kang SS, Ahn EH, Liu X, Bryson M, Miller GW, Weinshenker D, Ye K. 2021
ax0111 axoCells™ Human iPSC-Derived Neural Stem Cells, Alzheimer’s Disease (APOE4 HOM) female donor, ≥1.5 million cells 34958873 https://doi.org/10.1016/j.pneurobio.2021.102212 https://www.sciencedirect.com/science/article/abs/pii/S0301008221002264?via%3Dihub Neuronal ApoE4 stimulates C/EBPβ activation, promoting Alzheimer’s disease pathology in a mouse model Wang ZH, Xia Y, Wu Z, Kang SS, Zhang JC, Liu P, Liu X, Song W, Huin V, Dhaenens CM, Yu SP, Wang XC, Ye K. 2022
ax0111 axoCells™ Human iPSC-Derived Neural Stem Cells, Alzheimer’s Disease (APOE4 HOM) female donor, ≥1.5 million cells PMC10545487 https://doi.org/10.1016/j.stemcr.2023.08.002 https://www.cell.com/stem-cell-reports/pdf/S2213-6711(23)00301-6.pdf Astrocytic APOE4 genotype-mediated negative impacts on synaptic architecture in human pluripotent stem cell model Watanabe H, Murakami R, Tsumagari K, Morimoto S, Hashimoto T, Imaizumi K, Sonn I, Yamada K, Saito Y, Murayama S, Iwatsubo T, Okano H. 2023
ax0111 axoCells™ Human iPSC-Derived Neural Stem Cells, Alzheimer’s Disease (APOE4 HOM) female donor, ≥1.5 million cells PMC7463977 https://doi.org/10.3390/cells9081807 https://www.mdpi.com/2073-4409/9/8/1807/pdf?version=1596187789 Fyn Tyrosine Kinase Elicits Amyloid Precursor Protein Tyr682 Phosphorylation in Neurons from Alzheimer’s Disease Patients. Iannuzzi F, Sirabella R, Canu N, Maier TJ, Annunziato L, Matrone C. 2020
ax0112 axoCells™ Human iPSC-Derived Neural Stem Cells, Alzheimer’s Disease (PSEN1 L286V) female donor, ≥1.5 million cells PMC8758498 https://doi.org/10.1038/s41380-020-00956-4 https://www.nature.com/articles/s41380-020-00956-4.pdf C/EBPβ is a key transcription factor for APOE and preferentially mediates ApoE4 expression in Alzheimer’s disease Xia Y, Wang ZH, Zhang J, Liu X, Yu SP, Ye KX, Wang JZ, Ye K, Wang XC. 2020
ax0112 axoCells™ Human iPSC-Derived Neural Stem Cells, Alzheimer’s Disease (PSEN1 L286V) female donor, ≥1.5 million cells PMC10584868 https://doi.org/10.1038/s41467-023-42282-7 https://www.nature.com/articles/s41467-023-42282-7.pdf FSH and ApoE4 contribute to Alzheimer’s disease-like pathogenesis via C/EBPβ/δ-secretase in female mice Xiong J, Kang SS, Wang M, Wang Z, Xia Y, Liao J, Liu X, Yu SP, Zhang Z, Ryu V, Yuen T, Zaidi M, Ye K. 2023
ax0112 axoCells™ Human iPSC-Derived Neural Stem Cells, Alzheimer’s Disease (PSEN1 L286V) female donor, ≥1.5 million cells PMC8051868 https://doi.org/10.1126/sciadv.abe4499 https://www.science.org/doi/pdf/10.1126/sciadv.abe4499?download=true Netrin-1 receptor UNC5C cleavage by active δ-secretase enhances neurodegeneration, promoting Alzheimer’s disease pathologies. Chen G, Kang SS, Wang Z, Ahn EH, Xia Y, Liu X, Sandoval IM, Manfredsson FP, Zhang Z, Ye K. 2021
ax0112 axoCells™ Human iPSC-Derived Neural Stem Cells, Alzheimer’s Disease (PSEN1 L286V) female donor, ≥1.5 million cells PMC5467336 https://doi.org/10.1155/2017/1892612 https://downloads.hindawi.com/journals/np/2017/1892612.pdf Sortilin-Related Receptor Expression in Human Neural Stem Cells Derived from Alzheimer’s Disease Patients Carrying the APOE Epsilon 4 Allele Zollo A, Allen Z, Rasmussen HF, Iannuzzi F, Shi Y, Larsen A, Maier TJ, Matrone C. 2017
ax0113 axoCells™ Human iPSC-Derived Neural Stem Cells, Alzheimer’s Disease (PSEN1 M146L) male donor, ≥1.5 million cells PMC5386580 https://doi.org/10.1038/cddis.2017.89 https://www.nature.com/articles/cddis201789.pdf Aberrant iPSC-derived human astrocytes in Alzheimer’s disease. Jones VC, Atkinson-Dell R, Verkhratsky A, Mohamet L. 2017
ax0113 axoCells™ Human iPSC-Derived Neural Stem Cells, Alzheimer’s Disease (PSEN1 M146L) male donor, ≥1.5 million cells PMC9293911 https://doi.org/10.1038/s41398-022-02050-5 https://www.nature.com/articles/s41398-022-02050-5.pdf The effect of citalopram treatment on amyloid-β precursor protein processing and oxidative stress in human hNSC-derived neurons. Elsworthy RJ, Crowe JA, King MC, Dunleavy C, Fisher E, Ludlam A, Parri HR, Hill EJ, Aldred S. 2022
ax0113 axoCells™ Human iPSC-Derived Neural Stem Cells, Alzheimer’s Disease (PSEN1 M146L) male donor, ≥1.5 million cells PMC7463977 https://doi.org/10.3390/cells9081807 https://www.mdpi.com/2073-4409/9/8/1807/pdf?version=1596187789 Fyn Tyrosine Kinase Elicits Amyloid Precursor Protein Tyr682 Phosphorylation in Neurons from Alzheimer’s Disease Patients. Iannuzzi F, Sirabella R, Canu N, Maier TJ, Annunziato L, Matrone C. 2020
ax0114 axoCells™ Human iPSC-Derived Neural Stem Cells, Alzheimer’s Disease (PSEN1 A246E) female donor, ≥1.5 million cells PMC9293911 https://doi.org/10.1038/s41398-022-02050-5 https://www.nature.com/articles/s41398-022-02050-5.pdf The effect of citalopram treatment on amyloid-β precursor protein processing and oxidative stress in human hNSC-derived neurons Elsworthy RJ, Crowe JA, King MC, Dunleavy C, Fisher E, Ludlam A, Parri HR, Hill EJ, Aldred S. 2022
ax0114 axoCells™ Human iPSC-Derived Neural Stem Cells, Alzheimer’s Disease (PSEN1 A246E) female donor, ≥1.5 million cells PMC5467336 https://doi.org/10.1155/2017/1892612 https://downloads.hindawi.com/journals/np/2017/1892612.pdf Sortilin-Related Receptor Expression in Human Neural Stem Cells Derived from Alzheimer’s Disease Patients Carrying the APOE Epsilon 4 Allele Zollo A, Allen Z, Rasmussen HF, Iannuzzi F, Shi Y, Larsen A, Maier TJ, Matrone C. 2017
ax0114 axoCells™ Human iPSC-Derived Neural Stem Cells, Alzheimer’s Disease (PSEN1 A246E) female donor, ≥1.5 million cells PMC10929014 https://doi.org/10.3389/fnmol.2024.1365752 https://www.frontiersin.org/articles/10.3389/fnmol.2024.1365752/pdf?isPublishedV2=False LRRC25 expression during physiological aging and in mouse models of Alzheimer’s disease and iPSC-derived neurons. Devadoss D, Akkaoui J, Nair M, Lakshmana MK. 2024
ax0114 axoCells™ Human iPSC-Derived Neural Stem Cells, Alzheimer’s Disease (PSEN1 A246E) female donor, ≥1.5 million cells PMC7463977 https://doi.org/10.3390/cells9081807 https://www.mdpi.com/2073-4409/9/8/1807/pdf?version=1596187789 Fyn Tyrosine Kinase Elicits Amyloid Precursor Protein Tyr682 Phosphorylation in Neurons from Alzheimer’s Disease Patients. Iannuzzi F, Sirabella R, Canu N, Maier TJ, Annunziato L, Matrone C. 2020
ax0157 axoCells™ Human iPSC-Derived Sensory Neuron Cells, Media, Supplement and Coating kit, male donor, ≥0.5M cells PMC10802627 https://doi.org/10.1101/2024.01.10.575114 https://www.biorxiv.org/content/10.1101/2024.01.10.575114v1.full.pdf SARS-CoV-2 papain-like protease activates nociceptors to drive sneeze and pain Mali SS, Silva R, Gong Z, Cronce M, Vo U, Vuong C, Moayedi Y, Cox JS, Bautista DM 2024
ax0157 axoCells™ Human iPSC-Derived Sensory Neuron Cells, Media, Supplement and Coating kit, male donor, ≥0.5M cells 36244818 https://doi.org/10.1016/j.bja.2022.09.009 https://www.bjanaesthesia.org/action/showPdf?pii=S0007-0912%2822%2900519-0 Use of a human induced pluripotent stem cell-derived dorsal root ganglion neurone model to study analgesics in vitro: proof of principle using lidocaine Smulders PSH, Ten Hoope W, Bernardino Morcillo C, Hermanides J, Hollmann MW, Weber NC. 2022
ax0157 axoCells™ Human iPSC-Derived Sensory Neuron Cells, Media, Supplement and Coating kit, male donor, ≥0.5M cells 38640063 https://doi.org/10.1016/j.celrep.2024.114129 https://www.cell.com/cell-reports/pdf/S2211-1247(24)00457-1.pdf Macrophage epigenetic memories of early life injury drive neonatal nociceptive priming Dourson AJ, Fadaka AO, Warshak AM, Paranjpe A, Weinhaus B, Queme LF, Hofmann MC, Evans HM, Donmez OA, Forney C, Weirauch MT, Kottyan LC, Lucas D, Deepe GS Jr, Jankowski MP. 2024
ax0157 axoCells™ Human iPSC-Derived Sensory Neuron Cells, Media, Supplement and Coating kit, male donor, ≥0.5M cells 35478041 https://doi.org/10.1093/toxsci/kfac045 https://academic.oup.com/toxsci/article-pdf/188/1/131/45940430/kfac045.pdf In Vitro Pain Assay Using Human iPSC-Derived Sensory Neurons and Microelectrode Array Odawara A, Shibata M, Ishibashi Y, Nagafuku N, Matsuda N, Suzuki I. 2022
ax0157 axoCells™ Human iPSC-Derived Sensory Neuron Cells, Media, Supplement and Coating kit, male donor, ≥0.5M cells 37395585 https://doi.org/10.1111/exd.14870 https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/exd.14870 New human in vitro co-culture model of keratinocytes and sensory neurons like cells releasing substance P with an evaluation of the expression of ZIKV entry receptors: A potent opportunity to test Zika virus entry and to study Zika virus’ infection in neurons? Bocciarelli C, Cordel N, Leschiera R, Talagas M, Le Gall-Ianotto C, Hu W, Marcorelles P, Bellemere G, Bredif S, Fluhr J, Misery L, Lebonvallet N. 2023
ax0158 axoCells™ Human iPSC-Derived Sensory Neuron Media and Supplement kit 36244818 https://doi.org/10.1016/j.bja.2022.09.009 https://www.bjanaesthesia.org/action/showPdf?pii=S0007-0912%2822%2900519-0 Use of a human induced pluripotent stem cell-derived dorsal root ganglion neurone model to study analgesics in vitro: proof of principle using lidocaine Smulders PSH, Ten Hoope W, Bernardino Morcillo C, Hermanides J, Hollmann MW, Weber NC. 2022
ax0158 axoCells™ Human iPSC-Derived Sensory Neuron Media and Supplement kit 38640063 https://doi.org/10.1016/j.celrep.2024.114129 https://www.cell.com/cell-reports/pdf/S2211-1247(24)00457-1.pdf Macrophage epigenetic memories of early life injury drive neonatal nociceptive priming Dourson AJ, Fadaka AO, Warshak AM, Paranjpe A, Weinhaus B, Queme LF, Hofmann MC, Evans HM, Donmez OA, Forney C, Weirauch MT, Kottyan LC, Lucas D, Deepe GS Jr, Jankowski MP. 2024
ax0158 axoCells™ Human iPSC-Derived Sensory Neuron Media and Supplement kit 35478041 https://doi.org/10.1093/toxsci/kfac045 https://academic.oup.com/toxsci/article-pdf/188/1/131/45940430/kfac045.pdf In Vitro Pain Assay Using Human iPSC-Derived Sensory Neurons and Microelectrode Array Odawara A, Shibata M, Ishibashi Y, Nagafuku N, Matsuda N, Suzuki I. 2022
ax0158 axoCells™ Human iPSC-Derived Sensory Neuron Media and Supplement kit PMC10802627 https://doi.org/10.1101/2024.01.10.575114 https://www.biorxiv.org/content/10.1101/2024.01.10.575114v1.full.pdf SARS-CoV-2 papain-like protease activates nociceptors to drive sneeze and pain Mali SS, Silva R, Gong Z, Cronce M, Vo U, Vuong C, Moayedi Y, Cox JS, Bautista DM 2024
ax0158 axoCells™ Human iPSC-Derived Sensory Neuron Media and Supplement kit 37395585 https://doi.org/10.1111/exd.14870 https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/exd.14870 New human in vitro co-culture model of keratinocytes and sensory neurons like cells releasing substance P with an evaluation of the expression of ZIKV entry receptors: A potent opportunity to test Zika virus entry and to study Zika virus’ infection in neurons? Bocciarelli C, Cordel N, Leschiera R, Talagas M, Le Gall-Ianotto C, Hu W, Marcorelles P, Bellemere G, Bredif S, Fluhr J, Misery L, Lebonvallet N. 2023
ax0178 axoCells™ Human iPSC-Derived Motor Neuron Cells, Media and Supplement kit, male donor, ≥2 million cells PMC10760048 https://doi.org/10.1101/2023.12.12.571328 https://www.biorxiv.org/content/10.1101/2023.12.12.571328v1.full.pdf A high-fidelity CRISPR-Cas13 system improves abnormalities associated with C9ORF72-linked ALS/FTD. McCallister TX, Lim CKW, Terpstra WM, Alejandra Zeballos C M, Zhang S, Powell JE, Gaj T. 2023
ax0179 axoCells™ Motor Neuron Accelerator Supplement, 1 ml PMC10760048 https://doi.org/10.1101/2023.12.12.571328 https://www.biorxiv.org/content/10.1101/2023.12.12.571328v1.full.pdf A high-fidelity CRISPR-Cas13 system improves abnormalities associated with C9ORF72-linked ALS/FTD. McCallister TX, Lim CKW, Terpstra WM, Alejandra Zeballos C M, Zhang S, Powell JE, Gaj T. 2023
ax0211 axoCells™ Human iPSC-Derived Neural Stem Cells, Huntington’s Disease (HTT CAG50) female donor, ≥1.5 million cells PMC8891113 https://doi.org/10.1007/s10571-020-00984-2 https://link.springer.com/content/pdf/10.1007/s10571-020-00984-2.pdf A Progressive Loss of phosphoSer138-Profilin Aligns with Symptomatic Course in the R6/2 Mouse Model of Huntington’s Disease: Possible Sex-Dependent Signaling. Baharani A, Wei Z, Roesler WJ, Mousseau DD. 2022
ax0211 axoCells™ Human iPSC-Derived Neural Stem Cells, Huntington’s Disease (HTT CAG50) female donor, ≥1.5 million cells 32350390 https://doi.org/10.1038/s41380-020-0717-5 https://www.nature.com/articles/s41380-020-0717-5 ATP and spontaneous calcium oscillations control neural stem cell fate determination in Huntington’s disease: a novel approach for cell clock research Glaser T, Shimojo H, Ribeiro DE, Martins PPL, Beco RP, Kosinski M, Sampaio VFA, Corrêa-Velloso J, Oliveira-Giacomelli Á, Lameu C, de Jesus Santos AP, de Souza HDN, Teng YD, Kageyama R, Ulrich H. 2021
ax0211 axoCells™ Human iPSC-Derived Neural Stem Cells, Huntington’s Disease (HTT CAG50) female donor, ≥1.5 million cells PMC5146966 https://doi.org/10.1038/srep38856 https://www.nature.com/articles/srep38856.pdf High-throughput compound evaluation on 3D networks of neurons and glia in a microfluidic platform. Wevers NR, van Vught R, Wilschut KJ, Nicolas A, Chiang C, Lanz HL, Trietsch SJ, Joore J, Vulto P. 2016
ax0333 axoCells™ Human iPSC-Derived Striatal Neuron Media and Supplement kit 32350390 https://doi.org/10.1038/s41380-020-0717-5 https://www.nature.com/articles/s41380-020-0717-5 ATP and spontaneous calcium oscillations control neural stem cell fate determination in Huntington’s disease: a novel approach for cell clock research Glaser T, Shimojo H, Ribeiro DE, Martins PPL, Beco RP, Kosinski M, Sampaio VFA, Corrêa-Velloso J, Oliveira-Giacomelli Á, Lameu C, de Jesus Santos AP, de Souza HDN, Teng YD, Kageyama R, Ulrich H. 2021
ax0555 axoCells™ Human iPSC-Derived Sensory Neurons, male donor, ≥3.2 million cells 38640063 https://doi.org/10.1016/j.celrep.2024.114129 https://www.cell.com/cell-reports/pdf/S2211-1247(24)00457-1.pdf Macrophage epigenetic memories of early life injury drive neonatal nociceptive priming Dourson AJ, Fadaka AO, Warshak AM, Paranjpe A, Weinhaus B, Queme LF, Hofmann MC, Evans HM, Donmez OA, Forney C, Weirauch MT, Kottyan LC, Lucas D, Deepe GS Jr, Jankowski MP. 2024
ax0555 axoCells™ Human iPSC-Derived Sensory Neurons, male donor, ≥3.2 million cells PMC10802627 https://doi.org/10.1101/2024.01.10.575114 https://www.biorxiv.org/content/10.1101/2024.01.10.575114v1.full.pdf SARS-CoV-2 papain-like protease activates nociceptors to drive sneeze and pain Mali SS, Silva R, Gong Z, Cronce M, Vo U, Vuong C, Moayedi Y, Cox JS, Bautista DM 2024
ax0555 axoCells™ Human iPSC-Derived Sensory Neurons, male donor, ≥3.2 million cells PMC9761683 https://doi.org/10.1523/jneurosci.1630-22.2022 https://www.jneurosci.org/content/jneuro/42/49/9129.full.pdf The RNA-Binding Protein HuR Is Integral to the Function of Nociceptors in Mice and Humans. Kunder N, de la Peña JB, Lou TF, Chase R, Suresh P, Lawson J, Shukla T, Black B, Campbell ZT. 2022
ax0664 axoCells™ Human iPSC-Derived Microglia, male donor, ≥1 million cells 38366587 https://doi.org/10.1016/j.stem.2024.01.007 https://www.cell.com/action/showPdf?pii=S1934-5909%2824%2900008-0 Strengthening cardiac therapy pipelines using human pluripotent stem cell-derived cardiomyocytes. Raniga K, Nasir A, Vo NTN, Vaidyanathan R, Dickerson S, Hilcove S, Mosqueira D, Mirams GR, Clements P, Hicks R, Pointon A, Stebbeds W, Francis J, Denning C. 2024
ax0679 axoCells™ Human iPSC-Derived Microglia Cell, Media and Supplement kit, male donor, ≥1 million cells 38366587 https://doi.org/10.1016/j.stem.2024.01.007 https://www.cell.com/action/showPdf?pii=S1934-5909%2824%2900008-0 Strengthening cardiac therapy pipelines using human pluripotent stem cell-derived cardiomyocytes. Raniga K, Nasir A, Vo NTN, Vaidyanathan R, Dickerson S, Hilcove S, Mosqueira D, Mirams GR, Clements P, Hicks R, Pointon A, Stebbeds W, Francis J, Denning C. 2024
ax139789 (20 µg) axoCells™ Human Beta-NGF Supplement (20 µg) 38640063 https://doi.org/10.1016/j.celrep.2024.114129 https://www.cell.com/cell-reports/pdf/S2211-1247(24)00457-1.pdf Macrophage epigenetic memories of early life injury drive neonatal nociceptive priming Dourson AJ, Fadaka AO, Warshak AM, Paranjpe A, Weinhaus B, Queme LF, Hofmann MC, Evans HM, Donmez OA, Forney C, Weirauch MT, Kottyan LC, Lucas D, Deepe GS Jr, Jankowski MP. 2024
ax139789 (20 µg) axoCells™ Human Beta-NGF Supplement (20 µg) PMC9734133 https://doi.org/10.1038/s41598-022-23565-3 https://www.nature.com/articles/s41598-022-23565-3.pdf In vitro modelling of human proprioceptive sensory neurons in the neuromuscular system Badiola-Mateos M, Osaki T, Kamm RD, Samitier J. 2022
ax139789 (20 µg) axoCells™ Human Beta-NGF Supplement (20 µg) 35478041 https://doi.org/10.1093/toxsci/kfac045 https://academic.oup.com/toxsci/article-pdf/188/1/131/45940430/kfac045.pdf In Vitro Pain Assay Using Human iPSC-Derived Sensory Neurons and Microelectrode Array Odawara A, Shibata M, Ishibashi Y, Nagafuku N, Matsuda N, Suzuki I. 2022
ax139789 (20 µg) axoCells™ Human Beta-NGF Supplement (20 µg) 38195157 https://doi.org/10.1124/molpharm.123.000789 https://molpharm.aspetjournals.org/content/molpharm/105/3/233.full.pdf Pharmacologic Characterization of LTGO-33, a Selective Small Molecule Inhibitor of the Voltage-Gated Sodium Channel NaV1.8 with a Unique Mechanism of Action. Gilchrist JM, Yang ND, Jiang V, Moyer BD. 2024
ax139800 (10 µg) axoCells™ Human BDNF Supplement (10 µg) 38640063 https://doi.org/10.1016/j.celrep.2024.114129 https://www.cell.com/cell-reports/pdf/S2211-1247(24)00457-1.pdf Macrophage epigenetic memories of early life injury drive neonatal nociceptive priming Dourson AJ, Fadaka AO, Warshak AM, Paranjpe A, Weinhaus B, Queme LF, Hofmann MC, Evans HM, Donmez OA, Forney C, Weirauch MT, Kottyan LC, Lucas D, Deepe GS Jr, Jankowski MP. 2024
ax139800 (10 µg) axoCells™ Human BDNF Supplement (10 µg) 35478041 https://doi.org/10.1093/toxsci/kfac045 https://academic.oup.com/toxsci/article-pdf/188/1/131/45940430/kfac045.pdf In Vitro Pain Assay Using Human iPSC-Derived Sensory Neurons and Microelectrode Array Odawara A, Shibata M, Ishibashi Y, Nagafuku N, Matsuda N, Suzuki I. 2022
ax139800 (10 µg) axoCells™ Human BDNF Supplement (10 µg) PMC10760048 https://doi.org/10.1101/2023.12.12.571328 https://www.biorxiv.org/content/10.1101/2023.12.12.571328v1.full.pdf A high-fidelity CRISPR-Cas13 system improves abnormalities associated with C9ORF72-linked ALS/FTD. McCallister TX, Lim CKW, Terpstra WM, Alejandra Zeballos C M, Zhang S, Powell JE, Gaj T. 2023
ax139811 (10 µg) axoCells™ Human NT-3 Supplement (10 µg) 38640063 https://doi.org/10.1016/j.celrep.2024.114129 https://www.cell.com/cell-reports/pdf/S2211-1247(24)00457-1.pdf Macrophage epigenetic memories of early life injury drive neonatal nociceptive priming Dourson AJ, Fadaka AO, Warshak AM, Paranjpe A, Weinhaus B, Queme LF, Hofmann MC, Evans HM, Donmez OA, Forney C, Weirauch MT, Kottyan LC, Lucas D, Deepe GS Jr, Jankowski MP. 2024
ax139811 (10 µg) axoCells™ Human NT-3 Supplement (10 µg) PMC9734133 https://doi.org/10.1038/s41598-022-23565-3 https://www.nature.com/articles/s41598-022-23565-3.pdf In vitro modelling of human proprioceptive sensory neurons in the neuromuscular system Badiola-Mateos M, Osaki T, Kamm RD, Samitier J. 2022
ax139811 (10 µg) axoCells™ Human NT-3 Supplement (10 µg) 35478041 https://doi.org/10.1093/toxsci/kfac045 https://academic.oup.com/toxsci/article-pdf/188/1/131/45940430/kfac045.pdf In Vitro Pain Assay Using Human iPSC-Derived Sensory Neurons and Microelectrode Array Odawara A, Shibata M, Ishibashi Y, Nagafuku N, Matsuda N, Suzuki I. 2022
ax139855 (10 µg) axoCells™ Human GDNF Supplement (10µg) 38640063 https://doi.org/10.1016/j.celrep.2024.114129 https://www.cell.com/cell-reports/pdf/S2211-1247(24)00457-1.pdf Macrophage epigenetic memories of early life injury drive neonatal nociceptive priming Dourson AJ, Fadaka AO, Warshak AM, Paranjpe A, Weinhaus B, Queme LF, Hofmann MC, Evans HM, Donmez OA, Forney C, Weirauch MT, Kottyan LC, Lucas D, Deepe GS Jr, Jankowski MP. 2024
ax139855 (10 µg) axoCells™ Human GDNF Supplement (10µg) 35478041 https://doi.org/10.1093/toxsci/kfac045 https://academic.oup.com/toxsci/article-pdf/188/1/131/45940430/kfac045.pdf In Vitro Pain Assay Using Human iPSC-Derived Sensory Neurons and Microelectrode Array Odawara A, Shibata M, Ishibashi Y, Nagafuku N, Matsuda N, Suzuki I. 2022
ax139855 (10 µg) axoCells™ Human GDNF Supplement (10µg) PMC10760048 https://doi.org/10.1101/2023.12.12.571328 https://www.biorxiv.org/content/10.1101/2023.12.12.571328v1.full.pdf A high-fidelity CRISPR-Cas13 system improves abnormalities associated with C9ORF72-linked ALS/FTD. McCallister TX, Lim CKW, Terpstra WM, Alejandra Zeballos C M, Zhang S, Powell JE, Gaj T. 2023
ax139888 (20 µg) axoCells™ Human CNTF Supplement (20 µg) PMC8175425 https://doi.org/10.1038/s41598-021-91203-5 https://www.nature.com/articles/s41598-021-91203-5.pdf Bioengineered model of the human motor unit with physiologically functional neuromuscular junctions. Rimington RP, Fleming JW, Capel AJ, Wheeler PC, Lewis MP. 2021
ax139888 (20 µg) axoCells™ Human CNTF Supplement (20 µg) PMC10760048 https://doi.org/10.1101/2023.12.12.571328 https://www.biorxiv.org/content/10.1101/2023.12.12.571328v1.full.pdf A high-fidelity CRISPR-Cas13 system improves abnormalities associated with C9ORF72-linked ALS/FTD. McCallister TX, Lim CKW, Terpstra WM, Alejandra Zeballos C M, Zhang S, Powell JE, Gaj T. 2023
ax139888 (5 µg) axoCells™ Human CNTF Supplement (5 µg) PMC8175425 https://doi.org/10.1038/s41598-021-91203-5 https://www.nature.com/articles/s41598-021-91203-5.pdf Bioengineered model of the human motor unit with physiologically functional neuromuscular junctions. Rimington RP, Fleming JW, Capel AJ, Wheeler PC, Lewis MP. 2021
ax139888 (5 µg) axoCells™ Human CNTF Supplement (5 µg) PMC10760048 https://doi.org/10.1101/2023.12.12.571328 https://www.biorxiv.org/content/10.1101/2023.12.12.571328v1.full.pdf A high-fidelity CRISPR-Cas13 system improves abnormalities associated with C9ORF72-linked ALS/FTD. McCallister TX, Lim CKW, Terpstra WM, Alejandra Zeballos C M, Zhang S, Powell JE, Gaj T. 2023
ax2500 axoCells™ Human iPSC-Derived Ventricular Cardiomyocytes, Media, Supplement and Coating kit, male donor, ≥1 million cells 35789134 https://doi.org/10.1002/cpz1.462 https://currentprotocols.onlinelibrary.wiley.com/doi/pdfdirect/10.1002/cpz1.462 Software Tool for Automatic Quantification of Sarcomere Length and Organization in Fixed and Live 2D and 3D Muscle Cell Cultures In Vitro Stein JM, Arslan U, Franken M, de Greef JC, E Harding S, Mohammadi N, Orlova VV, Bellin M, Mummery CL, van Meer BJ. 2022
ax2500 axoCells™ Human iPSC-Derived Ventricular Cardiomyocytes, Media, Supplement and Coating kit, male donor, ≥1 million cells 33689843 https://doi.org/10.1016/j.taap.2021.115480 https://www.sciencedirect.com/science/article/pii/S0041008X21000879?via%3Dihub Improving reliability and reducing costs of cardiotoxicity assessments using laser-induced cell poration on microelectrode arrays Iachetta G, Colistra N, Melle G, Deleye L, Tantussi F, De Angelis F, Dipalo M. 2021
ax2500 axoCells™ Human iPSC-Derived Ventricular Cardiomyocytes, Media, Supplement and Coating kit, male donor, ≥1 million cells PMC8926344 https://doi.org/10.1126/sciadv.abl6367 https://ttu-ir.tdl.org/bitstreams/eafe7f8d-9277-4e2c-91ee-448f743360f8/download Membrane repair triggered by cholesterol-dependent cytolysins is activated by mixed lineage kinases and MEK Ray S, Roth R, Keyel PA. 2022
ax2500 axoCells™ Human iPSC-Derived Ventricular Cardiomyocytes, Media, Supplement and Coating kit, male donor, ≥1 million cells PMC7159882 https://doi.org/10.7554/elife.51453 https://elifesciences.org/articles/51453 Polyunsaturated fatty acid analogues differentially affect cardiac NaV, CaV, and KV channels through unique mechanisms Bohannon BM, de la Cruz A, Wu X, Jowais JJ, Perez ME, Dykxhoorn DM, Liin SI, Larsson HP. 2020
ax2508 axoCells™ Human iPSC-Derived Ventricular Cardiomyocytes, male donor, ≥1 million cells 35789134 https://doi.org/10.1002/cpz1.462 https://currentprotocols.onlinelibrary.wiley.com/doi/pdfdirect/10.1002/cpz1.462 Software Tool for Automatic Quantification of Sarcomere Length and Organization in Fixed and Live 2D and 3D Muscle Cell Cultures In Vitro Stein JM, Arslan U, Franken M, de Greef JC, E Harding S, Mohammadi N, Orlova VV, Bellin M, Mummery CL, van Meer BJ. 2022
ax2508 axoCells™ Human iPSC-Derived Ventricular Cardiomyocytes, male donor, ≥1 million cells 33689843 https://doi.org/10.1016/j.taap.2021.115480 https://www.sciencedirect.com/science/article/pii/S0041008X21000879?via%3Dihub Improving reliability and reducing costs of cardiotoxicity assessments using laser-induced cell poration on microelectrode arrays Iachetta G, Colistra N, Melle G, Deleye L, Tantussi F, De Angelis F, Dipalo M. 2021
ax2508 axoCells™ Human iPSC-Derived Ventricular Cardiomyocytes, male donor, ≥1 million cells PMC8926344 https://doi.org/10.1126/sciadv.abl6367 https://ttu-ir.tdl.org/bitstreams/eafe7f8d-9277-4e2c-91ee-448f743360f8/download Membrane repair triggered by cholesterol-dependent cytolysins is activated by mixed lineage kinases and MEK Ray S, Roth R, Keyel PA. 2022
ax2508 axoCells™ Human iPSC-Derived Ventricular Cardiomyocytes, male donor, ≥1 million cells PMC7159882 https://doi.org/10.7554/elife.51453 https://elifesciences.org/articles/51453 Polyunsaturated fatty acid analogues differentially affect cardiac NaV, CaV, and KV channels through unique mechanisms Bohannon BM, de la Cruz A, Wu X, Jowais JJ, Perez ME, Dykxhoorn DM, Liin SI, Larsson HP. 2020
ax2510 axoCells™ Human iPSC-Derived Atrial Cardiomyocytes, Media, Supplement and Coating kit, male donor, ≥1 million cells PMC10544075 https://doi.org/10.1016/j.jacbts.2023.05.007 https://www.sciencedirect.com/science/article/pii/S2452302X23002280?via%3Dihub Empagliflozin Suppresses the Differentiation/Maturation of Human Epicardial Preadipocytes and Improves Paracrine Secretome Profile Takano M, Kondo H, Harada T, Takahashi M, Ishii Y, Yamasaki H, Shan T, Akiyoshi K, Shuto T, Teshima Y, Wada T, Yufu K, Sako H, Anai H, Miyamoto S, Takahashi N. 2023
ax2510 axoCells™ Human iPSC-Derived Atrial Cardiomyocytes, Media, Supplement and Coating kit, male donor, ≥1 million cells PMC8050386 https://doi.org/10.1016/j.jbc.2021.100514 https://www.jbc.org/article/S0021-9258(21)00290-8/pdf Kv1.5 channels are regulated by PKC-mediated endocytic degradation Du Y, Wang T, Guo J, Li W, Yang T, Szendrey M, Zhang S. Kv1.5 channels are regulated by PKC-mediated endocytic degradation 2021
ax2510 axoCells™ Human iPSC-Derived Atrial Cardiomyocytes, Media, Supplement and Coating kit, male donor, ≥1 million cells PMC9910474 https://doi.org/10.1073/pnas.2212325120 https://www.pnas.org/doi/10.1073/pnas.2212325120 Mechanism of PKCε regulation of cardiac GIRK channel gating Gada KD, Chang M, Chandrashekar A, Plant LD, Noujaim SF, Logothetis DE. 2023
ax2518 axoCells™ Human iPSC-Derived Atrial Cardiomyocytes, male donor, ≥1 million cells PMC10544075 https://doi.org/10.1016/j.jacbts.2023.05.007 https://www.sciencedirect.com/science/article/pii/S2452302X23002280?via%3Dihub Empagliflozin Suppresses the Differentiation/Maturation of Human Epicardial Preadipocytes and Improves Paracrine Secretome Profile Takano M, Kondo H, Harada T, Takahashi M, Ishii Y, Yamasaki H, Shan T, Akiyoshi K, Shuto T, Teshima Y, Wada T, Yufu K, Sako H, Anai H, Miyamoto S, Takahashi N. 2023
ax2518 axoCells™ Human iPSC-Derived Atrial Cardiomyocytes, male donor, ≥1 million cells PMC8050386 https://doi.org/10.1016/j.jbc.2021.100514 https://www.jbc.org/article/S0021-9258(21)00290-8/pdf Kv1.5 channels are regulated by PKC-mediated endocytic degradation Du Y, Wang T, Guo J, Li W, Yang T, Szendrey M, Zhang S. Kv1.5 channels are regulated by PKC-mediated endocytic degradation 2021
ax2518 axoCells™ Human iPSC-Derived Atrial Cardiomyocytes, male donor, ≥1 million cells PMC9910474 https://doi.org/10.1073/pnas.2212325120 https://www.pnas.org/doi/10.1073/pnas.2212325120 Mechanism of PKCε regulation of cardiac GIRK channel gating Gada KD, Chang M, Chandrashekar A, Plant LD, Noujaim SF, Logothetis DE. 2023
ax2530-500 axoCells™ Cardiomyocyte Maintenance Media, 500mls 29045016 https://doi.org/10.1002/smll.201702677 https://flore.unifi.it/bitstream/2158/1102556/7/2158-1102556_preprint.pdf Liquid Crystalline Networks toward Regenerative Medicine and Tissue Repair. Martella D, Paoli P, Pioner JM, Sacconi L, Coppini R, Santini L, Lulli M, Cerbai E, Wiersma DS, Poggesi C, Ferrantini C, Parmeggiani C. 2017
ax2530-500 axoCells™ Cardiomyocyte Maintenance Media, 500mls NA https://doi.org/10.1016/j.cej.2022.140555 https://www.sciencedirect.com/science/article/pii/S1385894722060351?ssrnid=4233073&dgcid=SSRN_redirect_SD Sinusoidal stretchable fibrous electrodes regulate cardiac contraction Yanping Zhang, Alice Le Friec, Di Sun, Menglin Chen, 2023
ax2530-500 axoCells™ Cardiomyocyte Maintenance Media, 500mls PMC8050386 https://doi.org/10.1016/j.jbc.2021.100514 https://www.jbc.org/article/S0021-9258(21)00290-8/pdf Kv1.5 channels are regulated by PKC-mediated endocytic degradation Du Y, Wang T, Guo J, Li W, Yang T, Szendrey M, Zhang S. Kv1.5 channels are regulated by PKC-mediated endocytic degradation 2021
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ax3115 axoCells™ Human iPSC-Derived Striatal Neuron Cells, Media, Supplements and Coating kit, male donor, ≥1.5 million cells PMC4479615 https://doi.org/10.5966/sctm.2014-0083 https://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC4479615&blobtype=pdf In Vitro Differentiation of Human Neural Progenitor Cells Into Striatal GABAergic Neurons Lin L, Yuan J, Sander B, Golas MM. 2015
ax3118 axoCells™ Human iPSC-Derived Striatal Neuron Cells, Media, Supplements and Coating kit, male donor, ≥1.5 million cells 32350390 https://doi.org/10.1038/s41380-020-0717-5 https://www.nature.com/articles/s41380-020-0717-5 ATP and spontaneous calcium oscillations control neural stem cell fate determination in Huntington’s disease: a novel approach for cell clock research Glaser T, Shimojo H, Ribeiro DE, Martins PPL, Beco RP, Kosinski M, Sampaio VFA, Corrêa-Velloso J, Oliveira-Giacomelli Á, Lameu C, de Jesus Santos AP, de Souza HDN, Teng YD, Kageyama R, Ulrich H. 2021
ax3211 axoCells™ Human iPSC-Derived Striatal Neuron Cells, Media, Supplements and Coating kit, Huntington’s Disease (HTT CAG50) female donor, ≥1.5 million cells PMC8891113 https://doi.org/10.1007/s10571-020-00984-2 https://link.springer.com/content/pdf/10.1007/s10571-020-00984-2.pdf A Progressive Loss of phosphoSer138-Profilin Aligns with Symptomatic Course in the R6/2 Mouse Model of Huntington’s Disease: Possible Sex-Dependent Signaling. Baharani A, Wei Z, Roesler WJ, Mousseau DD. 2022
ax3211 axoCells™ Human iPSC-Derived Striatal Neuron Cells, Media, Supplements and Coating kit, Huntington’s Disease (HTT CAG50) female donor, ≥1.5 million cells 32350390 https://doi.org/10.1038/s41380-020-0717-5 https://www.nature.com/articles/s41380-020-0717-5 ATP and spontaneous calcium oscillations control neural stem cell fate determination in Huntington’s disease: a novel approach for cell clock research Glaser T, Shimojo H, Ribeiro DE, Martins PPL, Beco RP, Kosinski M, Sampaio VFA, Corrêa-Velloso J, Oliveira-Giacomelli Á, Lameu C, de Jesus Santos AP, de Souza HDN, Teng YD, Kageyama R, Ulrich H. 2021
ax3211 axoCells™ Human iPSC-Derived Striatal Neuron Cells, Media, Supplements and Coating kit, Huntington’s Disease (HTT CAG50) female donor, ≥1.5 million cells PMC5146966 https://doi.org/10.1038/srep38856 https://www.nature.com/articles/srep38856.pdf High-throughput compound evaluation on 3D networks of neurons and glia in a microfluidic platform. Wevers NR, van Vught R, Wilschut KJ, Nicolas A, Chiang C, Lanz HL, Trietsch SJ, Joore J, Vulto P. 2016
ax5111 axoCells™ Human iPSC-Derived Cortical Neuron Cells, Media, Supplements and Coating kit, Alzheimer’s Disease (APOE4 HOM) female donor, ≥1.5 million cells PMC8217363 https://doi.org/10.1007/s00401-021-02315-1 https://link.springer.com/article/10.1007/s00401-021-02315-1 ApoE4 inhibition of VMAT2 in the locus coeruleus exacerbates Tau pathology in Alzheimer’s disease Kang SS, Ahn EH, Liu X, Bryson M, Miller GW, Weinshenker D, Ye K. 2021
ax5111 axoCells™ Human iPSC-Derived Cortical Neuron Cells, Media, Supplements and Coating kit, Alzheimer’s Disease (APOE4 HOM) female donor, ≥1.5 million cells 34958873 https://doi.org/10.1016/j.pneurobio.2021.102212 https://www.sciencedirect.com/science/article/abs/pii/S0301008221002264?via%3Dihub Neuronal ApoE4 stimulates C/EBPβ activation, promoting Alzheimer’s disease pathology in a mouse model Wang ZH, Xia Y, Wu Z, Kang SS, Zhang JC, Liu P, Liu X, Song W, Huin V, Dhaenens CM, Yu SP, Wang XC, Ye K. 2022
ax5111 axoCells™ Human iPSC-Derived Cortical Neuron Cells, Media, Supplements and Coating kit, Alzheimer’s Disease (APOE4 HOM) female donor, ≥1.5 million cells PMC10545487 https://doi.org/10.1016/j.stemcr.2023.08.002 https://www.cell.com/stem-cell-reports/pdf/S2213-6711(23)00301-6.pdf Astrocytic APOE4 genotype-mediated negative impacts on synaptic architecture in human pluripotent stem cell model Watanabe H, Murakami R, Tsumagari K, Morimoto S, Hashimoto T, Imaizumi K, Sonn I, Yamada K, Saito Y, Murayama S, Iwatsubo T, Okano H. 2023
ax5111 axoCells™ Human iPSC-Derived Cortical Neuron Cells, Media, Supplements and Coating kit, Alzheimer’s Disease (APOE4 HOM) female donor, ≥1.5 million cells PMC7463977 https://doi.org/10.3390/cells9081807 https://www.mdpi.com/2073-4409/9/8/1807/pdf?version=1596187789 Fyn Tyrosine Kinase Elicits Amyloid Precursor Protein Tyr682 Phosphorylation in Neurons from Alzheimer’s Disease Patients. Iannuzzi F, Sirabella R, Canu N, Maier TJ, Annunziato L, Matrone C. 2020
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ax5113 axoCells™ Human iPSC-Derived Cortical Neuron Cells, Media, Supplements and Coating kit, Alzheimer’s Disease (PSEN1 M146L) male donor, ≥1.5 million cells PMC5386580 https://doi.org/10.1038/cddis.2017.89 https://www.nature.com/articles/cddis201789.pdf Aberrant iPSC-derived human astrocytes in Alzheimer’s disease. Jones VC, Atkinson-Dell R, Verkhratsky A, Mohamet L. 2017
ax5113 axoCells™ Human iPSC-Derived Cortical Neuron Cells, Media, Supplements and Coating kit, Alzheimer’s Disease (PSEN1 M146L) male donor, ≥1.5 million cells PMC9293911 https://doi.org/10.1038/s41398-022-02050-5 https://www.nature.com/articles/s41398-022-02050-5.pdf The effect of citalopram treatment on amyloid-β precursor protein processing and oxidative stress in human hNSC-derived neurons Elsworthy RJ, Crowe JA, King MC, Dunleavy C, Fisher E, Ludlam A, Parri HR, Hill EJ, Aldred S. 2022
ax5113 axoCells™ Human iPSC-Derived Cortical Neuron Cells, Media, Supplements and Coating kit, Alzheimer’s Disease (PSEN1 M146L) male donor, ≥1.5 million cells PMC7463977 https://doi.org/10.3390/cells9081807 https://www.mdpi.com/2073-4409/9/8/1807/pdf?version=1596187789 Fyn Tyrosine Kinase Elicits Amyloid Precursor Protein Tyr682 Phosphorylation in Neurons from Alzheimer’s Disease Patients. Iannuzzi F, Sirabella R, Canu N, Maier TJ, Annunziato L, Matrone C. 2020
ax5114 axoCells™ Human iPSC-Derived Cortical Neuron Cells, Media, Supplements and Coating kit, Alzheimer’s Disease (PSEN1 A246E) female donor, ≥1.5 million cells PMC9293911 https://doi.org/10.1038/s41398-022-02050-5 https://www.nature.com/articles/s41398-022-02050-5.pdf The effect of citalopram treatment on amyloid-β precursor protein processing and oxidative stress in human hNSC-derived neurons Elsworthy RJ, Crowe JA, King MC, Dunleavy C, Fisher E, Ludlam A, Parri HR, Hill EJ, Aldred S. 2022
ax5114 axoCells™ Human iPSC-Derived Cortical Neuron Cells, Media, Supplements and Coating kit, Alzheimer’s Disease (PSEN1 A246E) female donor, ≥1.5 million cells PMC5467336 https://doi.org/10.1155/2017/1892612 https://downloads.hindawi.com/journals/np/2017/1892612.pdf Sortilin-Related Receptor Expression in Human Neural Stem Cells Derived from Alzheimer’s Disease Patients Carrying the APOE Epsilon 4 Allele Zollo A, Allen Z, Rasmussen HF, Iannuzzi F, Shi Y, Larsen A, Maier TJ, Matrone C. 2017
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ax5114 axoCells™ Human iPSC-Derived Cortical Neuron Cells, Media, Supplements and Coating kit, Alzheimer’s Disease (PSEN1 A246E) female donor, ≥1.5 million cells PMC7463977 https://doi.org/10.3390/cells9081807 https://www.mdpi.com/2073-4409/9/8/1807/pdf?version=1596187789 Fyn Tyrosine Kinase Elicits Amyloid Precursor Protein Tyr682 Phosphorylation in Neurons from Alzheimer’s Disease Patients. Iannuzzi F, Sirabella R, Canu N, Maier TJ, Annunziato L, Matrone C. 2020
ax5115 axoCells™ Human iPSC-Derived Cortical Neuron Cells, Media, Supplements and Coating kit, male donor, ≥1.5 million cells PMC9860124 https://doi.org/10.1016/j.stemcr.2022.11.014 http://www.cell.com/article/S2213671122005471/pdf Long-term calcium imaging reveals functional development in hiPSC-derived cultures comparable to human but not rat primary cultures Estévez-Priego E, Moreno-Fina M, Monni E, Kokaia Z, Soriano J, Tornero D. 2023
ax5115 axoCells™ Human iPSC-Derived Cortical Neuron Cells, Media, Supplements and Coating kit, male donor, ≥1.5 million cells PMC5415290 https://doi.org/10.1177/2041731417697920 https://journals.sagepub.com/doi/pdf/10.1177/2041731417697920 Adapting tissue-engineered in vitro CNS models for high-throughput study of neurodegeneration. O’Rourke C, Lee-Reeves C, Drake RA, Cameron GW, Loughlin AJ, Phillips JB. 2017
ax5115 axoCells™ Human iPSC-Derived Cortical Neuron Cells, Media, Supplements and Coating kit, male donor, ≥1.5 million cells PMC9641809 https://doi.org/10.1186/s13578-022-00916-1 https://cellandbioscience.biomedcentral.com/counter/pdf/10.1186/s13578-022-00916-1 An increase in Semaphorin 3A biases the axonal direction and induces an aberrant dendritic arborization in an in vitro model of human neural progenitor differentiation Ferretti G, Romano A, Sirabella R, Serafini S, Maier TJ, Matrone C. 2022
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ax5116 axoCells™ Human iPSC-Derived Cortical Neuron Cells, Media, Supplements and Coating kit, female donor, ≥1.5 million cells 32314760 https://doi.org/10.1039/c9lc01209e https://pubs.rsc.org/en/content/articlepdf/2020/lc/c9lc01209e Development of two-photon polymerised scaffolds for optical interrogation and neurite guidance of human iPSC-derived cortical neuronal networks Crowe JA, El-Tamer A, Nagel D, Koroleva AV, Madrid-Wolff J, Olarte OE, Sokolovsky S, Estevez-Priego E, Ludl AA, Soriano J, Loza-Alvarez P, Chichkov BN, Hill EJ, Parri HR, Rafailov EU. 2020
ax5116 axoCells™ Human iPSC-Derived Cortical Neuron Cells, Media, Supplements and Coating kit, female donor, ≥1.5 million cells PMC9641809 https://doi.org/10.1186/s13578-022-00916-1 https://cellandbioscience.biomedcentral.com/counter/pdf/10.1186/s13578-022-00916-1 An increase in Semaphorin 3A biases the axonal direction and induces an aberrant dendritic arborization in an in vitro model of human neural progenitor differentiation Ferretti G, Romano A, Sirabella R, Serafini S, Maier TJ, Matrone C. 2022
ax5116 axoCells™ Human iPSC-Derived Cortical Neuron Cells, Media, Supplements and Coating kit, female donor, ≥1.5 million cells PMC8126955 https://doi.org/10.15252/embj.2020106798 https://onlinelibrary.wiley.com/doi/pdfdirect/10.15252/embj.2020106798 Centrosome-mediated microtubule remodeling during axon formation in human iPSC-derived neurons Lindhout FW, Portegies S, Kooistra R, Herstel LJ, Stucchi R, Hummel JJA, Scheefhals N, Katrukha EA, Altelaar M, MacGillavry HD, Wierenga CJ, Hoogenraad CC. 2021
ax5118 axoCells™ Human iPSC-Derived Cortical Neuron Cells, Media, Supplements and Coating kit, male donor, ≥1.5 million cells PMC9647772 https://doi.org/10.1038/s41380-022-01851-w https://www.nature.com/articles/s41380-022-01851-w.pdf Activation of a novel α2AAR-spinophilin-cofilin axis determines the effect of α2 adrenergic drugs on fear memory reconsolidation Saggu S, Chen Y, Cottingham C, Rehman H, Wang H, Zhang S, Augelli-Szafran C, Lu S, Lambert N, Jiao K, Lu XY, Wang Q. 2023
ax5118 axoCells™ Human iPSC-Derived Cortical Neuron Cells, Media, Supplements and Coating kit, male donor, ≥1.5 million cells PMC5467336 https://doi.org/10.1155/2017/1892612 https://downloads.hindawi.com/journals/np/2017/1892612.pdf Sortilin-Related Receptor Expression in Human Neural Stem Cells Derived from Alzheimer’s Disease Patients Carrying the APOE Epsilon 4 Allele Zollo A, Allen Z, Rasmussen HF, Iannuzzi F, Shi Y, Larsen A, Maier TJ, Matrone C. 2017
ax5118 axoCells™ Human iPSC-Derived Cortical Neuron Cells, Media, Supplements and Coating kit, male donor, ≥1.5 million cells PMC10929014 https://doi.org/10.3389/fnmol.2024.1365752 https://www.frontiersin.org/articles/10.3389/fnmol.2024.1365752/pdf?isPublishedV2=False LRRC25 expression during physiological aging and in mouse models of Alzheimer’s disease and iPSC-derived neurons Devadoss D, Akkaoui J, Nair M, Lakshmana MK. 2024
ax5118 axoCells™ Human iPSC-Derived Cortical Neuron Cells, Media, Supplements and Coating kit, male donor, ≥1.5 million cells PMC7498259 https://doi.org/10.7554/elife.58124 https://elifesciences.org/articles/58124 Quantitative mapping of transcriptome and proteome dynamics during polarization of human iPSC-derived neurons. Lindhout FW, Kooistra R, Portegies S, Herstel LJ, Stucchi R, Snoek BL, Altelaar AM, MacGillavry HD, Wierenga CJ, Hoogenraad CC. 2020
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