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Axol Bioscience supplies cells and custom laboratory services to model human disease. We spearhead the use of advanced in vitro methods and human pluripotent stem cell (hiPSC) technology for the generation of robust and physiologically relevant platforms for drug discovery.
Reliable, relevant, and robust.
It’s why we Science.
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Quality human iPSC-derived brain cells, immune cells and cardiomyocytes
Alzheimer's disease and frontotemporal dementia
Alzheimer’s disease (AD) is a neurodegenerative condition that is strongly linked with age and accounts for 60-70% of all cases of dementia. Early onset Alzheimer’s disease, which accounts for approximately 2-3% of AD cases, is a hereditary condition that is strongly associated with mutations in presenilin 1 (PSEN1), amyloid precursor protein (APP) and presenilin 2 (PSEN2) genes.
In vitro models of human disease
Investigating Alzheimer’s Disease progression without looking inside people’s heads:
We spoke with Selina Wray, Professor of Molecular Neuroscience and Alzheimer’s Research UK Senior Research Fellow in the Department of Neurodegenerative Disease at UCL Queen Square Institute of Neurology, London.
Selina explained how developing in vitro models of Alzheimer’s Disease using iPSC’s derived from patient cells will improve translation of therapies to the clinic for the treatment of this neurodegenerative disease.
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Who we are
Axol is transforming iPSC quality
Axol is a leading provider of product and service solutions in the iPSC-based neuroscience, immune cell, and cardiac modeling for drug discovery and screening markets. Our custom research capabilities in gene editing, electrophysiology, reprogramming, and differentiation means we can offer customers validated ready-to-use cell lines and a suite of services bolstered by deep scientific expertise and robust functional data – all with shorter lead times
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Customers across the globe
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