Human iPSC‑derived skin‑relevant models for active compound testing and research
Sensory neurons
Utilized in models of pain and sensation, including co-culture, microfluidics devices, organ-on-chip platforms and for in vitro disease modeling research. Exhibit functional relevance across multiple assays.
Acne and hyperseborrhea
Human iPSC‑derived sebocyte models recapitulate key sebocyte functions, including lipid synthesis, androgen responsiveness, inflammation, and response to C. acnes, arachidonic acid, and cannabinoids. Available in 2D and reconstructed 3D sebaceous gland formats.
Pigmentation, tanning, and lightening
Human iPSC‑derived melanocytes from multiple donor phototypes, support assays for melanogenesis, depigmentation, tanning, toxicity, and proliferation, with demonstrated melanosome production and transfer.
Candidate compound testing
Outsourced efficacy and toxicity testing using sebocyte, melanocyte, and sensory neuron models, with flexible assay design and physiologically relevant endpoints.
High‑content screening
Multiparametric readouts including lipid synthesis, pigmentation, cytokine release, receptor activation, neurite outgrowth, cell viability, and morphology across 96‑well and scalable screening formats.
iPSC lines from patients and unaffected donors
A diverse, well‑characterized human iPSC line library enabling scalable, reproducible manufacturing of dermatology‑relevant cell types. Lines support research across cosmetics, dermatology, pigmentation, acne, and neuro‑cosmetics.
iPSC-derived skin models for advanced in vitro modeling
Functionally validated sebocytes, melanocytes, and sensory neurons, suitable for monolayer, 3D, co‑culture, and microfluidic model formats.
Ensure confidence in your workflow with high-quality sebocytes differentiated from human induced pluripotent stem cells (iPSCs). Derived from consenting donor PBMCs, our sebocytes have been specifically developed for use in powerful in vitro monoculture models, and complex co-culture systems for drug discovery and cosmetics research
Sensory neurons
Ensure confidence in your workflow with high-quality axoCellsTM sensory neurons differentiated from human induced pluripotent stem cells (iPSCs). Derived from healthy consenting donor cord blood, our sensory neurons have been specifically developed for use in neurological microfluidics systems, nociception models and for assessing analgesic drug targets. Our robust, functionally-relevant sensory neurons express over 50 key ion channels and fuel world-leading microfluidic and “organ-on-chip” models.
Melanocytes
Ensure confidence in your workflow with high-quality Melanocytes differentiated from human induced pluripotent stem cells (iPSCs). Derived from consenting donors, our melanocytes have been specifically developed for use in powerful in vitro monoculture models, and complex co-culture systems for drug discovery and cosmetics research.
Specialist services
Services include manufacturing‑scale differentiation of iPSCs, quality control, cryopreservation, media optimisation, and custom workflows using our, client‑supplied, or third‑party iPSC lines. Automated, reproducible high‑throughput screening platforms for dermatology and cosmetic ingredient testing, supporting multi‑condition and multi‑endpoint studies with consistent physiologically relevant biology.
