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  5. Human iPSC-Derived Sensory Neuron Progenitors (Male) 3.2 x 10e6

Human iPSC-Derived Sensory Neuron Progenitors (Male) 3.2 x 10e6

product code: ax0055
From: $4,190.00

Please be aware that Neural Plating Medium ax0033 (not Xeno-Free) may be needed for your specific order. Please be sure to include ax0033 if required.

Product Quantity

Sensory Neuron Maturation Maximizer Medium Kit

Human/Murine/Rat BDNF

Human GDNF | ax139855 (10 µg)

Human beta-NGF

Human NT-3

SureBond-XF

Description

Human iPSC-Derived Sensory Neuron Progenitors (Male)

Axol Human iPSC-Sensory Neuron Progenitors are derived from integration-free iPSCs and have been differentiated to neurons using small molecules. We offer a fully optimized cell culture system including tailored Sensory Maintenance Medium and coating reagents to promote the viability and maturation of sensory neurons for endpoint assays on glass or plastic.

Our iPSC-derived sensory neurons express several voltage-gated sodium ion channels and transient receptor potential (TRP) ion channels that play a key role in nociception. These include sodium ion channels Nav1.7 and the DRG-specific, TTX-resistant channels, Nav1.8 and Nav1.9 as well as the temperature-sensitive, TRPV1 and TRPM8, and TRPA1, a sensor of pungency, bitterness and cold.

Axol iPSC-Derived Sensory Neuron Progenitors are available in large batch sizes for reliable and consistent results in high-throughput screening assays. The cells are also suitable for investigating disorders of the peripheral nervous system and chronic pain as well as drug targets for pain relief.

Product Specification

Starting material Cord blood CD34+ cells
Donor gender Male
Donor age at sampling Newborn
HLA serotype A29 A68, B38(Bw4) B44(Bw4), Cw8 Cw12
Karyotype Normal
Reprogramming method Episomal vector
Induction method Monolayer & chemically defined medium
Genetic modification None
Size 500,000 cells
Cell type iPSC-derived sensory neuron progenitors
Growth properties Adherent
Shipping conditions Dry ice
Storage conditions Vapor phase nitrogen

References

FAQS

Do you have any questions?

Yes, this is a necessary purification step. If you do not treat the cells with mitomycin C, then the flat non-sensory neuron cells would take over the culture.

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