With over a decade of experience in the human iPSC space, we understand that high-quality compound/phenotypic screening is challenging, with significant risks and costs if not performed well. But like you, we also see the enormous value in human iPSCs for building better, more physiologically relevant models of human disease.
That’s why we offer our iPSC expertise to leading biopharma and research organizations globally, helping them to generate robust pre-clinical data to validate compounds, or narrow down a large compound library for further in-depth experimental analysis.
We’ve developed a tried-and-tested workflow to offer efficientcompound screening to fit your project needs. We combine our iPSC expertise with a comprehensive suite of custom assays to deliver efficient compound/phenotypic screening, with a specific emphasis on the quality and communication of assay data.
Clients who work with Axol share our obsession with doing it once and doing it well. We prioritize quality control and robust data reporting, always built-in as standard in our projects, to ensure there are no surprise challenges (or costs), maximizing project success. That gives you more confidence, time and resource to focus on your research to produce better human disease models for drug discovery and beyond.
Choose an axoServicesTM Compound Screening project for:
Prioritization of quality and consistency
Open discussions with actual iPSC experts
Dependable, high-quality project outcomes
“Working with AXOL has been a professional experience all around. Data was delivered on time and presented in a clear and concise fashion. Our expectations were met, and we plan to work together again.”
Dr Ian Moench, GSK
What do you get with Axol?
Step 1. Kick-off meeting with the Axol iPSC experts
Decades of experience in the room
Open, two-way communication
Rapid follow-up with competitive quote
Step 2. Assay design and optimization
In-house expertise to guide design and maximize project success
Small-scale pilot experiments to optimize assay selection
Progression to higher throughput screening to enhance reproducibility
Step 3. Data analysis + reporting
Across the service project, all raw data is stored and lab notebooks are maintained in keeping with data management requirements
Full written report produced upon project completion with data-sharing meeting for full transparency
Step 4. Ongoing support
Continued communication and advice from iPSC experts
Ease the adaptation of cells into your experimental system
An open channel for future projects, collaborations and partnerships
We offer a bespoke service to fit your needs
Cellular imaging
ICC
Phagocytosis
Chemotaxis
Synaptic activity
Checking expression of additional marker genes by immunocytochemistry
Flow cytometry
Cell/protein profiling
Cell activation
Proliferation and viability
Protein and gene analysis
Enzymatic activity
Cytokine release
Protein interactions
qPCR and WB
ELISA/HTRF
Sequencing genomic regions of interest
Plate-based assays
Fluorescence
Luminescence
We also offer a bespoke MEA (Multi Electrode Array) service with decades of electrophysiology expertise in-house and an industry-leading MEA platform.
If you’d like to explore a compound screening project that isn’t listed above, please get in touch and we can discuss how to best assist you.
Our approach to collaboration
What does the ideal outsourced scientific project look like? We see ourselves as collaborators, partners, bench scientists and project managers, here to work alongside you to support and accelerate your work. And just like you, we like getting the work done efficiently and effectively, with clear open communication throughout.
We also recognize the trust you put in us to support your work, remove the heavy lifting and ensure your timelines proceed on schedule. Ultimately, we’re all progressing towards the same mission so we would be honored to partner on your research and get closer to delivering better therapies for patients.
Our company operates through its stated values and behaviors of Performance, Accountability, Transparency, Collaboration, Diversity & Inclusion and Integrity. With a dedicated services team, we’re always on hand to support in any way we can.
We hope that we can be of service and welcome your enquiries:
Fill in the form and let us know about your special requirements
