Frontotemporal dementia and Parkinson's Disease cellular models: In vitro characterization of pathological phenotypes in gene-edited iPSC-derived neurons with MAPT and LRRK2 mutations
MEAs have been adapted to drug discovery assays including cell-to-cell interaction, learning and memory, and network properties of neurons. High sensitivity consists key factor of their performance; it results in better signal to noise ratio leading to more reliable detection of action…
