Charcot-Marie-Tooth Disease

Charcot–Marie–Tooth disease (CMT) is a hereditary motor and sensory neuropathy of the peripheral nervous system characterized by progressive loss of muscle tissue and touch sensation across various parts of the body.

This disease is the most commonly inherited neurological disorder affecting about one in 2,500 people

Axol’s Charcot-Marie-Tooth disease (CMT) lines are derived from patients and are excellent models for investigating the disease.

Axol now offers made-to-order differentiated human iPS brain cells, such as motor and sensory neurons, from these CMT lines.

Charcot-Marie-Tooth Disease

Human iPSC-derived neural stem cells from Charcot-Marie-Tooth disease patients