Charcot-Marie-Tooth Disease

Charcot–Marie–Tooth disease (CMT) is a hereditary motor and sensory neuropathy of the peripheral nervous system characterized by progressive loss of muscle tissue and touch sensation across various parts of the body.

This disease is the most commonly inherited neurological disorder affecting about one in 2,500 people

Axol’s Charcot-Marie-Tooth disease (CMT) line is derived from a patient and is an excellent model for investigating the disease.

Axol now offers made-to-order differentiated cells, such as motor and sensory neurons, from this CMT line.

Charcot-Marie-Tooth Disease

Human iPSCs from a Charcot-Marie-Tooth disease patient