Description
Human iPSC-Derived Motor Neuron Progenitors
Axol Human iPSC-Derived Motor Neuron Progenitors are derived from a healthy male donor.
Axol iPSCs were differentiated to motor neuron progenitors using a combination of small molecules to regulate multiple signalling pathways. Initial expansion of iPSC-Motor Neuron Progenitors is possible before the terminal differentiation to motor neurons.
Axol Human iPSC-Derived Motor Neurons have been characterised by ICC and the motor neurons after 14 days in culture express HB9, LIM3, OLIG2 and TUJ1. After a further 14 days they express choline acetyltransferase (ChAT) and islet-1 (ISL1).
Product Specification
| Starting material | Fibroblasts |
| Donor gender | Male |
| Donor age at sampling | 74 yrs |
| Karyotype | Normal |
| Reprogramming method | Episomal vector |
| Induction method | Monolayer & chemically defined medium |
| Genetic modification | None |
| Size | 1 vial (≥2 million cells/ vial) |
| Growth properties | Adherent |
| Shipping conditions | Dry ice |
| Storage conditions | vapour phase nitrogen |
Resources
Technical Resources
FAQS
Do you have any questions?
Always filter the media after retinoic acid (RA) addition. Do not subject the RA aliquots to multiple freeze thaws RA is extremely light sensitive so protect the media with RA by wrapping the bottle/tube with foil.
We recommend using Vitronectin + Poly-D-Lysine (PDL). Please refer to the user guide for more information.
