Description
Human iPSC-Derived Motor Neuron Progenitors (C9ORF72 expansion)
Axol’s Human iPSC-Derived Motor Neuron Progenitors from a healthy male donor carrying C9orf72 hexanucleotide expansion. The repeat expansion of the parental iPSC line of the motor neuron progenitor was determined by Southern blot.
C9orf72 is present in ~ 40% of familial ALS and 8-10 % of sporadic ALS. It is the most common mutation related to ALS – far more common than SOD1 or TDP-43.
Product Specification
| Ethnicity | Caucasian (Ashkenazi) |
| Donor mutation | C9ORF72 repeat expansion |
| Starting material | Dermal fibroblast |
| Donor gender | Male |
| Donor age at sampling | 62 yrs |
| Reprogramming method | Sendai Virus |
| Size | ≥2 million cells |
| Shipping conditions | Dry ice |
| Storage conditions | Liquid nitrogen |
Resources
Technical Resources
FAQS
Do you have any questions?
Always filter the media after retinoic acid (RA) addition. Do not subject the RA aliquots to multiple freeze thaws RA is extremely light sensitive so protect the media with RA by wrapping the bottle/tube with foil.
For best results, use vitronectin
