Were you aware that iPSC-derived skin cells are having a big impact on research in the cosmetics and dermatology space? With forever challenges surrounding the availability, consistency, functionality and reproducibility of primary cells, researchers are turning to iPSC-derived cells.
The skin acts as a barrier against pathogens, UV radiation, and chemicals, while also regulating body temperature, preventing dehydration, and producing vitamin D. The skin not only shields against environmental stressors and microbial threats but also regulates body temperature and acts as a sensory interface.
Advanced models offer unparalleled insights into skin physiology, paving the way for effective, scientifically validated skincare solutions. As consumer demand for wellness-driven skincare continues to grow, so does the need for rigorous scientific validation. By integrating cutting-edge cell science with cosmetic innovation, we are redefining skincare— making it not only about appearance but also about true, long-lasting skin health.
Induced Pluripotent Stem Cell (iPSC) technology is a powerful tool for dermatology research and testing because it enables the creation of human skin models that closely mimic the physiology and responses of skin. Unlike primary cells, iPSC-derived cell lines can be used to produce a consistent supply of functional end-point cells, at high throughput, meaning you don’t have to waste time validating new batches of primary cells. As well as saving validation time, iPSC-derived cells are assay-ready more quickly than primary cells.
Axol’s iPSC-derived sebocytes and melanocytes are derived from multiple Caucasian, African, Asian and albino donors lines, both male and female, and can be used to validate specific claims. Differentiating iPSCs into the specialized cells needed to model skin requires technical expertise and a deep understanding of cellular biology.
Axol Bioscience, leader in iPSC technology for dermatology and cosmetics
At Axol we have integrated our unequalled knowledge of iPSCs with our strong pedigree within HTS in vitro testing, to develop powerful iPSC-derived cells and models to fuel dermatology research and cosmetic testing.
From Axol, you can purchase iPSC-derived cells:
- Melanocytes
- Sebocytes
- Sensory neurons
At Axol, we can run your screening and research projects:
- Modelling acne & hyperseborrhea
- Modelling pain and touch
- Modelling skin pigmentation
It’s conference season!
April and May are a busy time for our dermatology team, with three key skin and cosmetics conferences on the horizon:
- in-cosmetics global, Amsterdam, 8th-10th April
- Skin Summit, Antibes, 24th-25th April
- Cosmetotest, The International Preclinical and Clinical Testing Symposium, Lyon, 14th-15th May
Our team members will be attending these key meetings to keep up to date with the latest developments in the field and talk to delegates about their challenges in dermatology and cosmetics.
Learn more?
If you are interested in using iPSC-derived sebocytes to model acne, melanocytes for pigmentation studies, or want to take advantage of our unique range of HTS cell-based assays dedicated to skin research & ingredient testing, then come and speak to us at one of these meetings, or email on operations@axolbio.com and we’ll be happy to have a conversation.
To get you in the mood, download our new Dermatology flyer, with information on our, “More human, more consistent in vitro models for cosmetics and dermatology research”
