Dentaturobral-Pallidoluysian Atrophy

Dentatorubral-Pallidoluysian Atrophy (DRPLA) is an autosomal dominant spinocerebellar degeneration caused by an expansion of a CAG repeat encoding a polyglutamine tract in the atrophin-1 protein.

Axol cell lines derived from Dentatorubral-Pallidoluysian Atrophy patients are excellent models for investigating this rare inherited disease.

Axol now offers made-to-order human iPSC-derived brain cells from Dentatorubral-Pallidoluysian Atrophy patients.