axoServicesTM iPSC differentiation
Custom manufacturing of iPSC-derived cells
Custom iPSC differentiation services
Axol Bioscience provides custom differentiation of our iPSC lines, or client lines to generate physiologically relevant human cell models for research and drug discovery. Our custom manufacturing service supports scalable, high-quality generation and differentiation of iPSC-derived cells, enabling tailored, physiologically relevant models for specific research and drug discovery applications.
Outsource your iPSC differentiation project to the experts and prioritize quality, experience and confidence.
Extensive human iPSC line portfolio
- Library of >100 iPSC lines from unaffected and patient donors representing over twenty indications with particular focus on neurodegenerative disorders and ophthalmology
- Extensive quality control documentation and full commercial use ethical consents
- Collaboration with patient advocacy groups and PRISM ALS consortia
The library includes fully quality-controlled iPSC lines from unaffected and patient donors, including ALS, Alzheimer’s disease, Huntington’s disease, Parkinson’s disease, frontotemporal dementia, Friedreich’s ataxia, spinocerebellar ataxia, Nasu-Hakola disease and more, as well as multiple retinopathies, Leber congenital amaurosis and Ushers syndrome type 1.
Available cell types
Neuroscience
Cryopreserved functional cortical excitatory neurons, striatal neurons, cortical inhibitory interneurons, microglia, astrocytes and motor neurons shipped globally.
Ophthalmology
Functional and well-characterized retinal pigment epithelium (RPE) cells, retinal organoids (d60, d150, d180 and custom maturation) and microglia.
Cardiovascular
Functionally and phenotypically characterised iPSC-derived ventricular, left ventricular, and atrial cardiomyocytes exhibiting distinct chamber-specific ion-channel expression, contractile behaviour, and pharmacological responses.
Dermatology
Functionally validated sebocytes, melanocytes, and sensory neurons, suitable for monolayer, 3D, co-culture, and microfluidic model formats.
Custom differentiation capabilities
- Custom differentiation of our iPSC lines, or client lines to multiple neuronal and glial cell types.
- Custom differentiation of our iPSC lines, or client lines for retinal and ophthalmic research models, including retinal organoid generation.
- Manufacturing-scale differentiation of iPSCs to cardiac cells, quality control, cryopreservation, media optimisation, and custom workflows using our, client-supplied, or third-party iPSC lines.
- Manufacturing-scale differentiation of iPSCs, quality control, cryopreservation, media optimisation, and custom workflows using our, client-supplied, or third-party iPSC lines
Discuss your project
If you would like to discuss the adoption of iPSC-derived cells into your workflow, or our specialist services provision, please contact us at operations@axolbio.com