iPSCs and New Approach Methodologies (NAMs)
Technology Journal

If you want to see cutting-edge in vitro systems – it’s right here!

In collaboration with 12 leading platform and technology providers, Axol Bioscience has brought together a set of applications notes issued as an iPSC and MPS Tech Journal.

Learn how iPSC-derived cells in conjunction with advanced in vitro modalities and genomic and functional endpoints is generating a new era of more human relevant systems to push forward research and drug discovery. The journal looks at a range of MPS systems, organoid platforms and multi-electrode array and genomic and transcriptomic assays in conjunction with iPSC-derived neurons, sensory cells and cardiac cells.

The Tech Journal will be launched at the premier MPS conference, MPS 2025 in Brussels in June. We thank our collaborators and friends: 3Brain, BiomimiX, CytoTronics, Systasy Bioscience, Ushio, Mimetas, Sygnature Discovery, Axion BioSystems, 4DCell, innoVitro, NETRI, Tessara Therapeutics

For more details, contact operations@axolbio.com

Contents

  • Electrophysiological analysis of atrial and ventricular axoCells™ cardiomyocytes utilizing 3Brain’s CorePlate ™ enabled HD-MEA, 3Brain
  • Beating heart-on-chip to model atrial and ventricular cardiac chambers, BiomimiX
  • Advancing ALS Modeling: High-Dimensional Insights with CytoTronics’ Pixel, CytoTronics
  • Pathway Profiling of axoCells Sensory Neurons, Systasy Bioscience
  • Neurotoxicity Evaluation via Nerve MPS and Machine learning, Ushio
  • A 3D neurite outgrowth model for studying motor axon biology, Mimetas
  • A high content imaging screening assay to identify novel neuroinflammation modulators using human iPSC-derived microglia, Sygnature Discovery
  • Multi-electrode array characterization of a human iPSC-derived motor neuron disease model for ALS drug discovery, Axion BioSystems
  • SmartHeart: An innovative high-throughput assay to generate and assess cardiac micro tissues from hiPSCs, answering to the current challenges of cardiac toxicity and efficacy, 4DCell
  • AF on Demand: A Human iPSC-Derived Screening Assay Targeting Atrial Fibrillation, innoVitro
  • Characterizing sensory neurons as universal bio-digital sensor to explore PNS applications, NETRI
  • Poster: Development of iPSC-derived 3D human brain micro-tissues for drug discovery applications, Tessara Therapeutics