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Cortical Inhibitory Interneuron Progenitors (Male, newborn)



Early Access describes products in late stage of development and we welcome feedback on these products from the scientific community. These products are available to purchase at a discounted package price and will be supplied with a feedback form. Note, in Early Access the products will not have been manufactured at our ISO accredited facility and final protocols, documentation and literature may still be development.


Product code:
SKU: ax0667

Interneurons are the ‘brakes’ of the central nervous system. Connections between neurons in the brain are finely tuned and any increased electrical activity is dampened down by these cells. In the neocortex, the location for functions including sensory perceptions, emotion and cognition, interneurons represent between 20 and 30% of neurons.

axoCellsTM cortical inhibitory interneuron progenitors are derived from human iPSCs. In their progenitor state, the cells express the important Nkx-2.1 protein, indicative of mature parvalbumin and somatostatin interneuron development. After 20 days of culture, the cells mature to become interneurons. They will display key markers including parvalbumin, somatostatin, tyrosine hydroxylase, PAX-6, MAP2, beta-tubulin and GABA receptor and GAD enzyme. At day 30, the mature interneurons display functional calcium imaging responses to glutamic acid and glycine stimulation using the Axol NeurOne system.

Learn more about our Early Access Products and generate a quote


Under our Early Access program we are offering customers the following two options.

1.  When you purchase a co-culture* or tri-culture* kit, you will receive 1 x ax0667 and 1 x ax0662 interneurons free of charge.

2.  If you want to buy interneurons on their own, you can request a 50% discount on the purchase of a twin-pack of 1 x ax0667 and 1 x ax0662.

On participation, you agree to provide feedback through a quick six question form within two months of purchase.

No alternative discounts or product configurations available.

Email operations@axolbio.com for a quotation.

Culture Components

ax0667 Human iPSC-derived Cortical Inhibitory Interneuron Progenitors
ax0662 Human iPSC-derived Cortical Inhibitory Interneuron Progenitors
ax0031 Neural Maintenance Media
ax0033 Neural Plating Media
ax0674 NeurOne Cortical neuron supplement
ax0053 SureBond-XF
ax139800 (10 mg) Recombinant Human Brain-Derived Neurotrophic Factor (BDNF)

*For Co-Culture Kit add:

ax0015 Human iPSC-derived Neural Stem Cells

*For Tri-Culture Kit add:

ax0015 Human iPSC-derived Neural Stem Cells
ax0665 Human iPSC-derived Astrocytes

Product Specification

Starting material Fibroblasts
Donor gender Male
Donor age at sampling Newborn
Karyotype Normal
Reprogramming method Episomal vector
Induction method Monolayer & chemically defined medium
Genetic modification None
Size ≥2 million cells
Growth properties Adherent
Shipping conditions Dry ice


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