MyoMax Maturation Media (125 mL) optimized for the maturation of ventricular cardiomyocytes for cardiovascular research. Suitable for use with Ventricular (ax2508) Cardiomyocytes.
MyoMax: More Mature iPSC-derived cardiomyocytes
MyoMax offers a solution for a wide range of cardiac research and screening applications. This new add-on media is designed for use with axoCells ventricular cardiomyocytes and other iPSC-derived CMs.
A more mature phenotype in iPSC-CMs is evidenced by:
- Morphology: Increased numbers of rod-shaped cells, with superior sarcomere alignment.
- Marker Expression: The expression of key maturity markers and absence of immaturity markers
- Metabolic Shift: More mature CMs undergo a shift from glucose to fatty acid metabolism
- Electrophysiology: shorter action potential durations and faster conduction velocities closely reflect the electrophysiological properties of mature cardiac tissue.