Human iPSC-derived models for cosmetics and dermatology research

Human iPSC-derived models for cosmetics and dermatology research

Presented by: Hélène Leménager and Duncan Borthwick

The skin acts as a barrier against pathogens, UV radiation, and chemicals while also regulating body temperature, preventing dehydration, and producing vitamin D. The skin not only shields against environmental stressors and microbial threats but also regulates body temperature and acts as a sensory interface.

Advanced models offer unparalleled insights into skin physiology, paving the way for effective, scientifically validated skincare solutions. As consumer demand for wellness-driven skincare continues to grow, so does the need for rigorous scientific validation. By integrating cutting-edge cell science with cosmetic innovation, we are redefining skincare—making it not only about appearance but also about true, long-lasting skin health.

iPSC (Induced Pluripotent Stem Cell) technology is a powerful tool for dermatology research and testing, because it enables the creation of human skin models that closely mimic the physiology and responses of skin. With a consistent supply of functional end-point cells, iPSC-derived models support the development of safer and more effective products, allowing researchers to model skin diseases, test new skin care products, and develop therapeutic interventions without relying on animal testing.

Duncan Borthwick, our Head of Sales and Marketing, and Hélène Leménager, Head of Dermo-Cosmetics, discussed:

• How iPSC technology is a powerful tool for dermatology research and testing, enabling the creation of human skin models that closely mimic the physiology and responses of skin.
• iPSC-derived cell types we manufacture for cosmetics research, toxicology and drug discovery
• Our service project offerings for a wide range of tests, using in vitro models
• Compound testing and custom services