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A new set of iPSC-derived motor neurons for ALS drug discovery

Watch Webinar

A new set of iPSC-derived motor neurons for ALS drug discovery

Presented by: Hannah Sharplin

Axol Bioscience, leader in iPSC technology had launched the axoCells ALS Toolbox to support drug discovery and research into amyotrophic lateral sclerosis (ALS). The toolbox includes motor neurons from six different donor lines including two unaffected donors, one C9orf72 carrying donor (a sibling to one of the ALS donors), and three donors each carrying significant genotypes associated with ALS, SOD1, C9orf72 and TDP43.

These cells have been characterized by histology / ICC and neuronal activity as measured by spontaneous neuronal activity (SNA) and multi-electrode array (MEA) plus reproducibility data where they show reproducible characteristic phenotypes related to ALS hyperexcitability.

Watch this webinar to learn more about this new set of iPSC-derived motor neurons and their application to support ALS / MND drug discovery and research.