Axol’s cerebral cortical neural stem cells (NSCs) are derived from integration-free, induced pluripotent stem cells (iPSCs) under fully defined neural induction conditions.
Axol Human iPSC-Derived Neural Stem Cells express typical markers of cerebral cortical neural stem and progenitor cells such as PAX6 and FOXG1. They spontaneously form polarized neural rosette structures when cultured as a monolayer. Additionally, Axol’s NSCs can generate cortical neurons that are electrically active and have the ability to form functional synapses and neural circuits in vitro.