Fibroblasts isolated from normal, healthy tissues such as skin, mammary, lung, kidney and muscle tissue.
Skin fibroblasts from patients with particular diseases such as Parkinson’s Disease, Huntington’s Disease, cancer and diabetes.
Fully defined, serum-free fibroblast culture medium
Fibroblast cell culture medium developed by Axol. It’s completely defined so is reliable and consistent for your crucial experiments.
Wound healing, collagen & ECM production, paracrine signalling, reprogramming...
Human fibroblasts, also known as stromal cells, have a wide range of fascinating cellular functions and practical applications. Fibroblasts are important cells that secrete a diverse range of paracrine factors that affect cell and tissue homeostasis.
Stromal cells secrete extracellular matrix components such as collagens and can remodel the ECM. They are often used as feeder cells to culture other cell types at low density and in co-culture studies to explore the effects of secreted growth factors or cytokines on processes such as wound healing and hormone signaling. Cancer-associated fibroblasts (CAFs) play a role in tumor growth and metastasis, and are being investigated as potential targets for cancer therapy. Fibroblasts can be reprogrammed to induced pluripotent stem cells (iPSCs) that can undergo directed differentiation to a multitude of cell types that resemble primary cells.
Normal human fibroblasts isolated from healthy tissues.
“Our cells arrived last week and that we are highly pleased with them. Everything went fine, the cells arrived on time and in good condition. They are growing really nicely. I want to thank you for all your help!”
– Sanda Raic, Mediterranean Institute of Life Sciences. September 2015.
Dermal fibroblasts isolated from patients with particular diseases. These cells can be used for reprogramming and directed differentiation in order to generate in vitro models of the disease for screening novel drugs and drug combinations.
Our Fibroblast Cell Culture Medium (ax3103-500) is a fully defined media, containing no animal components or human plasma components. It contains only recombinant and synthetic components.
This ensures minimal variability for your experiments. The media is fully supplemented and ready to use.
“Our lab LOVES the fibroblast media!!! We are finally having success with our primary fibroblasts after months of trouble shooting problems with cell growth (I think it was the FBS we were using). We now call it “Magic Fairy Media”!”
– Randi Garcia, University of New Mexico. November 2015.
Custom cell & tissue sourcing
Can’t find what you’re looking for? Our custom cell & tissue sourcing service can help you find primary human cells or tissue from healthy and patient donors. Simply tell us your specifications and we will endeavour to meet your requirements.