Dental pulp stem cells (DPSCs) are tissue-specific adult stem cells that share properties of mesenchymal stem cells. They have proliferative capacity and can undergo directed differentiation to multiple cell lineages including odontoblasts, osteoblasts, chondrocytes and adipocytes. Dental pulp stem cells are thought to arise from neural crest cells and they can be directed to differentiate to neurons and Schwann-like cells.
Axol Dental Pulp Stem Cells are derived from a healthy female donor and are cryopreserved at passage 2. The DPSCs are >90% positive for the markers CD29, CD44, CD90, CD105 and are <10% positive for the markers CD34 and CD45. The cells are proliferative and can be passaged up to 3 times further in Axol Dental Pulp Stem Cell Culture Medium. The dental pulp stem cells have been validated for lineage-specific differentiation using Axol osteogenesis, chondrogenesis or adipogenesis differentiation media.