Genome Editing

Genetically edited iPSC-derived models can help researchers better understand how specific genes contribute to disease pathogenesis at the molecular and cellular level in a tissue-specific nature.

Furthermore, they represent valuable platforms for identifying drug targets and studying drug mechanisms of action, paving the way for developing new therapeutic interventions for many genetic diseases that are currently untreatable.

Our custom cellular reprograming service and directed differentiation of iPSCs offers the possibility of generating many disease models from any genetic background.

By combining the power of CRISPR-Cas9 genome editing with our iPSC technology, we can create accurate cellular models of genetic conditions by introducing disease-causing mutations into healthy control cell lines.

We can also correct those mutations in genomes of patient-derived cells to provide the matched control cell line.