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Functional characterisation of human iPSC-derived atrial cardiomyocytes

Functional characterisation of human iPSC-derived atrial cardiomyocytes

Here we outline our results from studies to validate human induced pluripotent stem cell-derived atrial cardiomyocytes (hiPSC-ACMs) generated by Axol Bioscience. The atrial phenotype of Axol hiPSC-ACMs was first characterised at the molecular level using immunocytochemistry with atrial specific markers before functional validation using manual patch clamp recordings of action potential (AP) parameters.