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Immune response and as indicators of various inflammatory diseases, monocytes and macrophages are vital cells to study for biomedical researchers. Further understanding the behaviours of these cells will not only help to elucidate immunological mechanisms but potentially uncover new compounds to facilitate disease diagnoses.
Below we share the remarkable journey of a monocyte to macrophage as an essential component of the immune response, and explore how you can successfully use monocytes and macrophages in your research.
Daniel Rock, Microglia Application Specialist at Axol Bioscience, will cover different areas, such as:
- Developing a scalable and reproducible generation of physiologically-relevant microglia
- Validation of robust, disease-relevant assays
- Building a translatable neurodegeneration model: longitudinal monitoring of healthy and patient donor iPSC co-cultures
- Assessing the contribution of astrocytes and microglia to the neuroinflammatory microenvironment