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Peripheral Nervous System Cells

Axol offers healthy and diseased sensory and motor neuron human induced pluripotent stem cells (iPSCs) to enable an understanding of neurological disease pathways and progression

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Human iPSC-derived neural stem cells from healthy donors

Human iPSC-derived neural stem cells from healthy donors

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Peripheral Nervous System

Axol iPSC-derived sensory and motor neuron progenitors are available in large batch sizes for reliable and consistent results in high-throughput screening assays.

We’ve used our expertise in neural differentiation to bring you human dorsal root ganglion (DRG) neurons derived from induced pluripotent stem cells (iPSCs). Axol Human iPSC-Sensory Neuron Progenitors are derived from integration-free iPSCs and have been differentiated to neurons using small molecules. We also offer a fully optimized cell culture system including tailored Sensory Neuron Maintenance Medium, Sensory Neuron Maturation Maximizer and coating reagents to promote the viability and maturation of sensory neurons for endpoint assays on glass or plastic within three weeks.

We have specifically developed Motor Neuron Recovery Medium which supports cell recovery after thawing and initial progenitor cell expansion, as well as Motor Neuron Maintenance Medium and Motor Neuron Maturation Accelerator supplement which promotes the optimal differentiation and maturation of motor neurons within three weeks. We have also developed human iPSC-derived motor neuron progenitors from both healthy and patient donors,

All cell types can be cultured in vitro to provide physiologically relevant alternatives to conventional animal-derived models for use in proof-of-principle drug-screening assays and for modeling motor neuron degeneration and disorders of the peripheral nervous system such as chronic pain.