Products
Human Intrahepatic Biliary Epithelial Cells
N/A
500,000 cells *Lot dependent. Please inquire for latest lot quantity and price*
Primary Human Liver Sinusoidal Endothelial Cells (Mix Population)
N/A
>500.000 cells/vial *Lot dependent. Please inquire for latest lot quantity and price*
Primary Human Hepatic Stellate Cells
N/A
100,000 cells *Lot dependent. Please inquire for latest lot quantity and price*
Information
Liver Cells
Our primary hepatocytes have been validated for CYP induction. Data on the fold induction of CYP1A2, CYP2B6 and CYP3A4 are generated for each lot of cells and is stated in the Certificate of Analysis for each order. They have post-thaw viability and plateability of >70%. We also offer purified hepatic stellate cells, intra-hepatic biliary epithelial cells and cryopreserved human Kupffer cells.
Assay-Ready Expanded (ARE) hepatocytes are cryopreserved human hepatocytes that are easy to plate and ready to use for a wide range of applications including hepatic metabolism, compound uptake, CYP induction/inhibition, hepatotoxicity, genotoxicity and 3D co-culture studies. ARE Hepatocytes express CYP enzymes, are metabolically functional, are polarized and can be infected by the Hepatitis C virus.
ARE Hepatocytes are primary human hepatocytes that have been expanded via activation of the Oncostatin M pathway. Large batch sizes of hepatocytes from the same donor are available on request, providing a reliable and consistent source of primary hepatocytes. ARE Hepatocytes should be used directly for endpoint assays and cannot be expanded further since de-differentiation may occur.
