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Immune Cells

Axol Human iPSC-Derived Microglia are derived from iPSCs that have undergone an intermediate differentiation to monocytes prior to directed terminal differentiation to microglia.



Immune Cells

Axol Microglia are highly pure and consistently reproducible populations of cells. The Human iPSC-derived Cryopreserved Microglia are shown to be highly phagocytic in nature and equivalent to fresh cells.

Phagocytosis is used as a primary measure of functional Microglia activity. The Cryopreserved Microglia (ax0668) exhibit bait-dependent phagocytosis when exposed to fluorescent pHrodo-labelled bait including beta-amyloid and alpha synuclein.