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Immune Cells

Axol Human iPSC-Derived Microglia are derived from iPSCs that have undergone an intermediate differentiation to monocytes prior to directed terminal differentiation to microglia.

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Immune Cells

Axol Microglia are highly pure and consistently reproducible populations of cells. The Human iPSC-derived Cryopreserved Microglia are shown to be highly phagocytic in nature and equivalent to fresh cells.

Phagocytosis is used as a primary measure of functional Microglia activity. The Cryopreserved Microglia (ax0668) exhibit bait-dependent phagocytosis when exposed to fluorescent pHrodo-labelled bait including beta-amyloid and alpha synuclein.